Beyond the Symptom: The Biology of Fatigue.

dc.contributor.authorRaizen, David M
dc.contributor.authorMullington, Janet
dc.contributor.authorAnaclet, Christelle
dc.contributor.authorClarke, Gerard
dc.contributor.authorCritchley, Hugo
dc.contributor.authorDantzer, Robert
dc.contributor.authorDavis, Ronald
dc.contributor.authorDrew, Kelly L
dc.contributor.authorFessel, Josh
dc.contributor.authorFuller, Patrick M
dc.contributor.authorGibson, Erin M
dc.contributor.authorHarrington, Mary
dc.contributor.authorLipkin, W Ian
dc.contributor.authorKlerman, Elizabeth B
dc.contributor.authorKlimas, Nancy
dc.contributor.authorKomaroff, Anthony L
dc.contributor.authorKoroshetz, Walter
dc.contributor.authorKrupp, Lauren
dc.contributor.authorKuppuswamy, Anna
dc.contributor.authorLasselin, Julie
dc.contributor.authorLewis, Laura D
dc.contributor.authorMagistretti, Pierre J.
dc.contributor.authorMatos, Heidi Y
dc.contributor.authorMiaskowski, Christine
dc.contributor.authorMiller, Andrew H
dc.contributor.authorNath, Avindra
dc.contributor.authorNedergaard, Maiken
dc.contributor.authorOpp, Mark R
dc.contributor.authorRitchie, Marylyn D
dc.contributor.authorRogulja, Dragana
dc.contributor.authorRolls, Asya
dc.contributor.authorSalamone, John D
dc.contributor.authorSaper, Clifford
dc.contributor.authorWhittemore, Vicky
dc.contributor.authorWylie, Glenn
dc.contributor.authorYounger, Jarred
dc.contributor.authorZee, Phyllis C
dc.contributor.authorHeller, H Craig
dc.contributor.departmentBioscience Program
dc.contributor.departmentKAUST Smart Health Initiative
dc.contributor.departmentBiological and Environmental Science and Engineering (BESE) Division
dc.contributor.institutionDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, USA.
dc.contributor.institutionDepartment of Neurology, Harvard Medical School, Boston, MA, USA.
dc.contributor.institutionDepartment of Neurological Surgery, University of California, Davis School of Medicine, Sacramento, CA, USA.
dc.contributor.institutionDepartment of Psychiatry and Neurobehavioural Science, and APC Microbiome Ireland, University College Cork, Cork, Ireland.
dc.contributor.institutionBrighton and Sussex Medical School Department of Neuroscience, University of Sussex, Brighton, UK.
dc.contributor.institutionDepartment of Symptom Research, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
dc.contributor.institutionDepartment of Biochemistry and Genetics, Stanford University, Palo Alto, CA, USA.
dc.contributor.institutionInstitute of Arctic Biology, Center for Transformative Research in Metabolism, University of Alaska Fairbanks, Fairbanks, AK, USA.
dc.contributor.institutionDivision of Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA.
dc.contributor.institutionDepartment of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA, USA.
dc.contributor.institutionNeuroscience Program, Smith College, Northampton, MA, USA.
dc.contributor.institutionCenter for Infection and Immunity, and Department of Neurology and Pathology, Columbia University, New York City, NY, USA.
dc.contributor.institutionDepartment of Neurology, Massachusetts General Hospital; Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA.
dc.contributor.institutionDepartment of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
dc.contributor.institutionDepartment of Clinical Immunology, College of Osteopathic Medicine, Nova Southeastern University, Ft. Lauderdale, FL, USA.
dc.contributor.institutionNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
dc.contributor.institutionDepartment of Neurology, NYU Grossman School of Medicine, NYC, NY, USA.
dc.contributor.institutionUniversity College London, Queen Square Institute of Neurology, London, England.
dc.contributor.institutionDepartment of Psychology, Stockholm University, Stockholm, Sweden.
dc.contributor.institutionCenter for Systems Neuroscience, Department of Biomedical Engineering, Boston University, Boston, MA, USA.
dc.contributor.institutionDepartment of Physiological Nursing, School of Nursing, University of California, San Francisco, San Francisco, CA, USA.
dc.contributor.institutionDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
dc.contributor.institutionDepartment of Neurology and Neurosurgery, University of Rochester Medical Center, Rochester, NY, USA.
dc.contributor.institutionDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA.
dc.contributor.institutionDepartment of Genetics, Institute for Biomedical Informatics, Penn Center for Precision Medicine, University of Pennsylvania, Philadelphia, PA, USA.
dc.contributor.institutionDepartment of Neurobiology, Harvard University, Boston, MA, USA.
dc.contributor.institutionRappaport Institute for Medical Research, Technion, Israel Institute of Technology, Haifa, Israel.
dc.contributor.institutionDepartment of Psychological Sciences, University of Connecticut, Storrs, CT, USA.
dc.contributor.institutionRocco Ortenzio Neuroimaging Center at Kessler Foundation, East Hanover, NJ, USA.
dc.contributor.institutionDepartment of Psychology, University of Alabama, Birmingham, Birmingham, AL, USA.
dc.contributor.institutionCenter for Circadian and Sleep Medicine, Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
dc.contributor.institutionDepartment of Biology, Stanford University and Sleep Research Society, Stanford, CA, USA.
dc.date.accessioned2023-05-25T05:58:21Z
dc.date.available2023-05-25T05:58:21Z
dc.date.issued2023-05-24
dc.description.abstractA workshop titled "Beyond the Symptom: The Biology of Fatigue" was held virtually September 27-28, 2021. It was jointly organized by the Sleep Research Society and the Neurobiology of Fatigue Working Group of the NIH Blueprint Neuroscience Research Program. For access to the presentations and video recordings, see: https : //neuroscienceblueprint.nih.gov/about/event/beyond-symptom-biology-fatigue. The goals of this workshop were to bring together clinicians and scientists who use a variety of research approaches to understand fatigue in multiple conditions and to identify key gaps in our understanding of the biology of fatigue. This workshop summary distills key issues discussed in this workshop and provides a list of promising directions for future research on this topic. We do not attempt to provide a comprehensive review of the state of our understanding of fatigue, nor to provide a comprehensive reprise of the many excellent presentations. Rather, our goal is to highlight key advances and to focus on questions and future approaches to answering them.
dc.description.sponsorshipThis report was written by experts who attended and presented at the workshop. Opinions expressed by the authors, however, do not represent the policy or position of the NIH. We are grateful to the NIH Blueprint Neuroscience Research Program for their financial support of the workshop. David M Raizen is funded by the National Institute of Neurological Disease and Stroke (NINDS) of the National Institutes of Health (NIH) under award number: R01NS122779 and by a Department of Defense (DoD) under award number W81XWH-22-1-0069. Janet Mullington is funded by the National Heart, Lung, and Blood Institute (NHLBI) of the NIH under award number: R01HL125379. C Anaclet has no Financial or Non-Financial Disclosures; she is funded by NINDS of the NIH under award number: R01NS073613 and by the BrightFocus Foundation. Christelle Anaclet is funded by NINDS of the NIH under award number: R01NS073613 and by the BrightFocus Foundation. Robert Dantzer is funded by the National Cancer Institute (NCI) of the NIH under award number: R01 CA193522. Ron Davis receives funding from the Open Medicine Foundation, the ARPA Foundation, donations from patients and caregivers, and is funded by the National Institute of Allergy and Infectious Diseases (NIAID) of the NIH under award number: R01AI139550. Kelly L Drew and has received research support from Be Cool Pharmaceutics for work unrelated to this project and is funded by the National Institute of General Medical Sciences (NIGMS) of the NIH under award number: P20GM130443. Patrick M Fuller is funded by NINDS of the NIH under award numbers: R01NS103161 and R01NS073613 and by NHLBI of the NIH under award number: P01HL149630. Erin M Gibson is funded by NCI of the NIH under award number: R21CA267135, by NINDS of the NIH under award number: R01NS126610, and the DoD under award number: W81XWH2110846. Mary Harrington is funded by the NIGMS of the NIH under award number: R15 GM126545. W Ian Lipkin is funded by NIAID of the NIH under award number: U54AI138370-06. Elizabeth B Klerman is funded by NINDS of the NIH under award numbers R01-NS099055, U01-NS114001, R01-NS114526-02S1, by the National Institute of Aging (NIA) of the NIH under award number: U54-AG062322, by the National Institute of Drug Abuse of the NIH under award number R21-DA052861, by the National Institute of Child Health and Human Development (NICHD) of the NIH under award number: R01- HD107064; by the DoD under award number: W81XWH201076; and by the Leducq Trans-Atlantic Network of Excellence On Circadian Effects in Stroke. Anthony L Komaroff is funded by NIAID of the NIH under award number: 1U54AI138370. Anna Kuppuswamy is funded by Wellcome Trust under award number: 202346/Z/16/Z. Lauren D Lewis is funded by NIA of the NIH under award number: R01AG070135, by the National Center for Complementary and Integrative Health (NCCIH) of the NIH under award number: R01AT011429, and by NINDS of the NIH under award number R21NS123412. Maiken Nedergaard is funded by NINDS of the NIH under award numbers: RF1NS110049 and U19NS128613 and by NCCIH of the NIH under award number: R01AT011439. Mark R Opp is funded by the NIA of the NIH under award number: R01AG064465, and by the DoD under award number: W81XXWH221084. Dragana Rogulja is funded by The New York Stem Cell Foundation. A Rolls is funded by the European Research Council (ERC) STG-NEIMO. John D Salamone is funded by the National Institute of Mental Health (NIMH) of the NIH under the award number: R01MH121350, and by Otsuka, and the University of Connecticut Research Foundation. Clifford Saper is funded by NINDS of the NIH under award number: R01 NS072337, by NIMH of the NIH under award number: R01 MH112714, by NHLBI under award number: P01 HL149630, and by a subcontract from the University of Tsukuba, Japan. Glenn Wylie is funded by the Department of Veterans' Affairs under award number: 5I01CX000893, by the National Multiple Sclerosis Society under award number: RG 4232A1, and by the New Jersey Commission for Brain Injury Research under award number: 10.005.BIR1. Jarred Younger is funded by NINDS of the NIH under award number: R01-NS109529, and by the DoD under award number W81XWH-19-1-0725. Phyllis C Zee is funded by NHLBI of the NIH under award number: R01HL140580, by NIA of the NIH under award numbers: P01AG011412, R01AG059291 and R01AG068579, and by NICHD of the NIH under award number: R01HD097786. The workshop was supported by funding from the NIH Blueprint Neuroscience Research Program. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
dc.eprint.versionPost-print
dc.identifier.citationRaizen, D. M., Mullington, J., Anaclet, C., Clarke, G., Critchley, H., Dantzer, R., Davis, R., Drew, K. L., Fessel, J., Fuller, P. M., Gibson, E. M., Harrington, M., Lipkin, W. I., Klerman, E. B., Klimas, N., Komaroff, A. L., Koroshetz, W., Krupp, L., Kuppuswamy, A., … Heller, H. C. (2023). Beyond the Symptom: The Biology of Fatigue. SLEEP. https://doi.org/10.1093/sleep/zsad069
dc.identifier.doi10.1093/sleep/zsad069
dc.identifier.issn0161-8105
dc.identifier.journalSleep
dc.identifier.pmid37224457
dc.identifier.urihttp://hdl.handle.net/10754/692035
dc.relation.urlhttps://academic.oup.com/sleep/advance-article/doi/10.1093/sleep/zsad069/7177603
dc.rightsThis is an accepted manuscript version of a paper before final publisher editing and formatting. The version of record is available from Sleep.
dc.rights.embargodate2024-05-24
dc.titleBeyond the Symptom: The Biology of Fatigue.
dc.typeArticle
display.details.left<span><h5>Embargo End Date</h5>2024-05-24<br><br><h5>Type</h5>Article<br><br><h5>Authors</h5><a href="https://repository.kaust.edu.sa/search?query=orcid.id:0000-0001-5935-0476&spc.sf=dc.date.issued&spc.sd=DESC">Raizen, David M</a> <a href="https://orcid.org/0000-0001-5935-0476" target="_blank"><img src="https://repository.kaust.edu.sa/server/api/core/bitstreams/82a625b4-ed4b-40c8-865a-d6a5225a26a4/content" width="16" height="16"/></a><br><a href="https://repository.kaust.edu.sa/search?query=orcid.id:0000-0002-9156-9424&spc.sf=dc.date.issued&spc.sd=DESC">Mullington, Janet</a> <a href="https://orcid.org/0000-0002-9156-9424" target="_blank"><img src="https://repository.kaust.edu.sa/server/api/core/bitstreams/82a625b4-ed4b-40c8-865a-d6a5225a26a4/content" width="16" height="16"/></a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Anaclet, Christelle,equals">Anaclet, Christelle</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Clarke, Gerard,equals">Clarke, Gerard</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Critchley, Hugo,equals">Critchley, Hugo</a><br><a href="https://repository.kaust.edu.sa/search?query=orcid.id:0000-0001-9399-6107&spc.sf=dc.date.issued&spc.sd=DESC">Dantzer, Robert</a> <a href="https://orcid.org/0000-0001-9399-6107" target="_blank"><img src="https://repository.kaust.edu.sa/server/api/core/bitstreams/82a625b4-ed4b-40c8-865a-d6a5225a26a4/content" width="16" height="16"/></a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Davis, Ronald,equals">Davis, Ronald</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Drew, Kelly L,equals">Drew, Kelly L</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Fessel, Josh,equals">Fessel, Josh</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Fuller, Patrick M,equals">Fuller, Patrick M</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Gibson, Erin M,equals">Gibson, Erin M</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Harrington, Mary,equals">Harrington, Mary</a><br><a href="https://repository.kaust.edu.sa/search?query=orcid.id:0000-0002-8768-9386&spc.sf=dc.date.issued&spc.sd=DESC">Lipkin, W Ian</a> <a href="https://orcid.org/0000-0002-8768-9386" target="_blank"><img src="https://repository.kaust.edu.sa/server/api/core/bitstreams/82a625b4-ed4b-40c8-865a-d6a5225a26a4/content" width="16" height="16"/></a><br><a href="https://repository.kaust.edu.sa/search?query=orcid.id:0000-0002-7402-3171&spc.sf=dc.date.issued&spc.sd=DESC">Klerman, Elizabeth B</a> <a href="https://orcid.org/0000-0002-7402-3171" target="_blank"><img src="https://repository.kaust.edu.sa/server/api/core/bitstreams/82a625b4-ed4b-40c8-865a-d6a5225a26a4/content" width="16" height="16"/></a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Klimas, Nancy,equals">Klimas, Nancy</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Komaroff, Anthony L,equals">Komaroff, Anthony L</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Koroshetz, Walter,equals">Koroshetz, Walter</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Krupp, Lauren,equals">Krupp, Lauren</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Kuppuswamy, Anna,equals">Kuppuswamy, Anna</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Lasselin, Julie,equals">Lasselin, Julie</a><br><a 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href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Miller, Andrew H,equals">Miller, Andrew H</a><br><a href="https://repository.kaust.edu.sa/search?query=orcid.id:0000-0003-0927-5855&spc.sf=dc.date.issued&spc.sd=DESC">Nath, Avindra</a> <a href="https://orcid.org/0000-0003-0927-5855" target="_blank"><img src="https://repository.kaust.edu.sa/server/api/core/bitstreams/82a625b4-ed4b-40c8-865a-d6a5225a26a4/content" width="16" height="16"/></a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Nedergaard, Maiken,equals">Nedergaard, Maiken</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Opp, Mark R,equals">Opp, Mark R</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Ritchie, Marylyn D,equals">Ritchie, Marylyn D</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Rogulja, Dragana,equals">Rogulja, Dragana</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Rolls, Asya,equals">Rolls, Asya</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Salamone, John D,equals">Salamone, John D</a><br><a href="https://repository.kaust.edu.sa/search?query=orcid.id:0000-0002-5788-3014&spc.sf=dc.date.issued&spc.sd=DESC">Saper, Clifford</a> <a href="https://orcid.org/0000-0002-5788-3014" target="_blank"><img src="https://repository.kaust.edu.sa/server/api/core/bitstreams/82a625b4-ed4b-40c8-865a-d6a5225a26a4/content" width="16" height="16"/></a><br><a href="https://repository.kaust.edu.sa/search?query=orcid.id:0000-0002-3980-9451&spc.sf=dc.date.issued&spc.sd=DESC">Whittemore, Vicky</a> <a href="https://orcid.org/0000-0002-3980-9451" target="_blank"><img src="https://repository.kaust.edu.sa/server/api/core/bitstreams/82a625b4-ed4b-40c8-865a-d6a5225a26a4/content" width="16" height="16"/></a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Wylie, Glenn,equals">Wylie, Glenn</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Younger, Jarred,equals">Younger, Jarred</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Zee, Phyllis C,equals">Zee, Phyllis C</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.author=Heller, H Craig,equals">Heller, H Craig</a><br><br><h5>KAUST Department</h5><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.department=Bioscience Program,equals">Bioscience Program</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.department=KAUST Smart Health Initiative,equals">KAUST Smart Health Initiative</a><br><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.department=Biological and Environmental Science and Engineering (BESE) Division,equals">Biological and Environmental Science and Engineering (BESE) Division</a><br><br><h5>Date</h5>2023-05-24</span>
display.details.right<span><h5>Abstract</h5>A workshop titled "Beyond the Symptom: The Biology of Fatigue" was held virtually September 27-28, 2021. It was jointly organized by the Sleep Research Society and the Neurobiology of Fatigue Working Group of the NIH Blueprint Neuroscience Research Program. For access to the presentations and video recordings, see: https : //neuroscienceblueprint.nih.gov/about/event/beyond-symptom-biology-fatigue. The goals of this workshop were to bring together clinicians and scientists who use a variety of research approaches to understand fatigue in multiple conditions and to identify key gaps in our understanding of the biology of fatigue. This workshop summary distills key issues discussed in this workshop and provides a list of promising directions for future research on this topic. We do not attempt to provide a comprehensive review of the state of our understanding of fatigue, nor to provide a comprehensive reprise of the many excellent presentations. Rather, our goal is to highlight key advances and to focus on questions and future approaches to answering them.<br><br><h5>Citation</h5>Raizen, D. M., Mullington, J., Anaclet, C., Clarke, G., Critchley, H., Dantzer, R., Davis, R., Drew, K. L., Fessel, J., Fuller, P. M., Gibson, E. M., Harrington, M., Lipkin, W. I., Klerman, E. B., Klimas, N., Komaroff, A. L., Koroshetz, W., Krupp, L., Kuppuswamy, A., … Heller, H. C. (2023). Beyond the Symptom: The Biology of Fatigue. SLEEP. https://doi.org/10.1093/sleep/zsad069<br><br><h5>Acknowledgements</h5>This report was written by experts who attended and presented at the workshop. Opinions expressed by the authors, however, do not represent the policy or position of the NIH. We are grateful to the NIH Blueprint Neuroscience Research Program for their financial support of the workshop. David M Raizen is funded by the National Institute of Neurological Disease and Stroke (NINDS) of the National Institutes of Health (NIH) under award number: R01NS122779 and by a Department of Defense (DoD) under award number W81XWH-22-1-0069. Janet Mullington is funded by the National Heart, Lung, and Blood Institute (NHLBI) of the NIH under award number: R01HL125379. C Anaclet has no Financial or Non-Financial Disclosures; she is funded by NINDS of the NIH under award number: R01NS073613 and by the BrightFocus Foundation. Christelle Anaclet is funded by NINDS of the NIH under award number: R01NS073613 and by the BrightFocus Foundation. Robert Dantzer is funded by the National Cancer Institute (NCI) of the NIH under award number: R01 CA193522. Ron Davis receives funding from the Open Medicine Foundation, the ARPA Foundation, donations from patients and caregivers, and is funded by the National Institute of Allergy and Infectious Diseases (NIAID) of the NIH under award number: R01AI139550. Kelly L Drew and has received research support from Be Cool Pharmaceutics for work unrelated to this project and is funded by the National Institute of General Medical Sciences (NIGMS) of the NIH under award number: P20GM130443. Patrick M Fuller is funded by NINDS of the NIH under award numbers: R01NS103161 and R01NS073613 and by NHLBI of the NIH under award number: P01HL149630. Erin M Gibson is funded by NCI of the NIH under award number: R21CA267135, by NINDS of the NIH under award number: R01NS126610, and the DoD under award number: W81XWH2110846. Mary Harrington is funded by the NIGMS of the NIH under award number: R15 GM126545. W Ian Lipkin is funded by NIAID of the NIH under award number: U54AI138370-06. Elizabeth B Klerman is funded by NINDS of the NIH under award numbers R01-NS099055, U01-NS114001, R01-NS114526-02S1, by the National Institute of Aging (NIA) of the NIH under award number: U54-AG062322, by the National Institute of Drug Abuse of the NIH under award number R21-DA052861, by the National Institute of Child Health and Human Development (NICHD) of the NIH under award number: R01- HD107064; by the DoD under award number: W81XWH201076; and by the Leducq Trans-Atlantic Network of Excellence On Circadian Effects in Stroke. Anthony L Komaroff is funded by NIAID of the NIH under award number: 1U54AI138370. Anna Kuppuswamy is funded by Wellcome Trust under award number: 202346/Z/16/Z. Lauren D Lewis is funded by NIA of the NIH under award number: R01AG070135, by the National Center for Complementary and Integrative Health (NCCIH) of the NIH under award number: R01AT011429, and by NINDS of the NIH under award number R21NS123412. Maiken Nedergaard is funded by NINDS of the NIH under award numbers: RF1NS110049 and U19NS128613 and by NCCIH of the NIH under award number: R01AT011439. Mark R Opp is funded by the NIA of the NIH under award number: R01AG064465, and by the DoD under award number: W81XXWH221084. Dragana Rogulja is funded by The New York Stem Cell Foundation. A Rolls is funded by the European Research Council (ERC) STG-NEIMO. John D Salamone is funded by the National Institute of Mental Health (NIMH) of the NIH under the award number: R01MH121350, and by Otsuka, and the University of Connecticut Research Foundation. Clifford Saper is funded by NINDS of the NIH under award number: R01 NS072337, by NIMH of the NIH under award number: R01 MH112714, by NHLBI under award number: P01 HL149630, and by a subcontract from the University of Tsukuba, Japan. Glenn Wylie is funded by the Department of Veterans' Affairs under award number: 5I01CX000893, by the National Multiple Sclerosis Society under award number: RG 4232A1, and by the New Jersey Commission for Brain Injury Research under award number: 10.005.BIR1. Jarred Younger is funded by NINDS of the NIH under award number: R01-NS109529, and by the DoD under award number W81XWH-19-1-0725. Phyllis C Zee is funded by NHLBI of the NIH under award number: R01HL140580, by NIA of the NIH under award numbers: P01AG011412, R01AG059291 and R01AG068579, and by NICHD of the NIH under award number: R01HD097786. The workshop was supported by funding from the NIH Blueprint Neuroscience Research Program. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.<br><br><h5>Journal</h5><a href="https://repository.kaust.edu.sa/search?spc.sf=dc.date.issued&spc.sd=DESC&f.journal=Sleep,equals">Sleep</a><br><br><h5>DOI</h5><a href="https://doi.org/10.1093/sleep/zsad069">10.1093/sleep/zsad069</a><br><br><h5>PubMed ID</h5><a href="https://www.ncbi.nlm.nih.gov/pubmed/37224457">37224457</a><br><br><h5>Additional Links</h5>https://academic.oup.com/sleep/advance-article/doi/10.1093/sleep/zsad069/7177603</span>
kaust.personMagistretti, Pierre J.
orcid.authorRaizen, David M::0000-0001-5935-0476
orcid.authorMullington, Janet::0000-0002-9156-9424
orcid.authorAnaclet, Christelle
orcid.authorClarke, Gerard
orcid.authorCritchley, Hugo
orcid.authorDantzer, Robert::0000-0001-9399-6107
orcid.authorDavis, Ronald
orcid.authorDrew, Kelly L
orcid.authorFessel, Josh
orcid.authorFuller, Patrick M
orcid.authorGibson, Erin M
orcid.authorHarrington, Mary
orcid.authorLipkin, W Ian::0000-0002-8768-9386
orcid.authorKlerman, Elizabeth B::0000-0002-7402-3171
orcid.authorKlimas, Nancy
orcid.authorKomaroff, Anthony L
orcid.authorKoroshetz, Walter
orcid.authorKrupp, Lauren
orcid.authorKuppuswamy, Anna
orcid.authorLasselin, Julie
orcid.authorLewis, Laura D
orcid.authorMagistretti, Pierre J.::0000-0002-6678-320X
orcid.authorMatos, Heidi Y::0000-0002-5486-0773
orcid.authorMiaskowski, Christine
orcid.authorMiller, Andrew H
orcid.authorNath, Avindra::0000-0003-0927-5855
orcid.authorNedergaard, Maiken
orcid.authorOpp, Mark R
orcid.authorRitchie, Marylyn D
orcid.authorRogulja, Dragana
orcid.authorRolls, Asya
orcid.authorSalamone, John D
orcid.authorSaper, Clifford::0000-0002-5788-3014
orcid.authorWhittemore, Vicky::0000-0002-3980-9451
orcid.authorWylie, Glenn
orcid.authorYounger, Jarred
orcid.authorZee, Phyllis C
orcid.authorHeller, H Craig
orcid.id0000-0002-3980-9451
orcid.id0000-0002-5788-3014
orcid.id0000-0003-0927-5855
orcid.id0000-0002-5486-0773
orcid.id0000-0002-6678-320X
orcid.id0000-0002-7402-3171
orcid.id0000-0002-8768-9386
orcid.id0000-0001-9399-6107
orcid.id0000-0002-9156-9424
orcid.id0000-0001-5935-0476
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