Molecular insights into the Darwin paradox of coral reefs from the sea anemone Aiptasia
Salazar Moya, Octavio Ruben
Presnell, Jason S.
Cleves, Phillip A.
Liew, Yi Jin
Krediet, Cory J.
Cziesielski, Maha Joana
Voolstra, Christian R.
Weis, Virginia M.
Pringle, John R.
KAUST DepartmentCore Labs, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.
DARWIN21, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.
Red Sea Research Center (RSRC)
Biological and Environmental Science and Engineering (BESE) Division
Computational Bioscience Research Center (CBRC)
Sanger and Third Generation Sequencing
NGS, qPCR and Single Cell Genomics
Computer, Electrical and Mathematical Science and Engineering (CEMSE) Division
Center for Desert Agriculture
Marine Science Program
Permanent link to this recordhttp://hdl.handle.net/10754/690422
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AbstractSymbiotic cnidarians such as corals and anemones form highly productive and biodiverse coral reef ecosystems in nutrient-poor ocean environments, a phenomenon known as Darwin’s paradox. Resolving this paradox requires elucidating the molecular bases of efficient nutrient distribution and recycling in the cnidarian-dinoflagellate symbiosis. Using the sea anemone Aiptasia, we show that during symbiosis, the increased availability of glucose and the presence of the algae jointly induce the coordinated up-regulation and relocalization of glucose and ammonium transporters. These molecular responses are critical to support symbiont functioning and organism-wide nitrogen assimilation through glutamine synthetase/glutamate synthase–mediated amino acid biosynthesis. Our results reveal crucial aspects of the molecular mechanisms underlying nitrogen conservation and recycling in these organisms that allow them to thrive in the nitrogen-poor ocean environments.
CitationCui, G., Konciute, M. K., Ling, L., Esau, L., Raina, J.-B., Han, B., Salazar, O. R., Presnell, J. S., Rädecker, N., Zhong, H., Menzies, J., Cleves, P. A., Liew, Y. J., Krediet, C. J., Sawiccy, V., Cziesielski, M. J., Guagliardo, P., Bougoure, J., Pernice, M., … Aranda, M. (2023). Molecular insights into the Darwin paradox of coral reefs from the sea anemone Aiptasia. Science Advances, 9(11). https://doi.org/10.1126/sciadv.adf7108
SponsorsThis work was supported by KAUST baseline funds, Gordon and Betty Moore Foundation grant #2629.01, and Simons Foundation grant LIFE#336932.
PubMed Central IDPMC10017044
CollectionsArticles; Biological and Environmental Science and Engineering (BESE) Division; Red Sea Research Center (RSRC); Bioscience Program; Marine Science Program; Computational Bioscience Research Center (CBRC); Center for Desert Agriculture; Computer, Electrical and Mathematical Science and Engineering (CEMSE) Division
Except where otherwise noted, this item's license is described as Archived with thanks to Science Advances under a Creative Commons license, details at: https://creativecommons.org/licenses/by-nc/4.0/
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