The first case of artemisinin treatment failure of plasmodium falciparum imported to Oman from Tanzania

Subudhi, Amit; Bienvenu, Anne-Lise; Bonnot, Guillaume; Abu-Shamma, Reem; Khamis, Faryal; Lawati, Hussain Ali Abdulhussain Al; Picot, Stephane; Petersen, Eskild; Pain, Arnab

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Article

Date

2022-08-12

Embargo End Date

2023-08-12

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http://hdl.handle.net/10754/680259

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Abstract

We present the clinical and genomic epidemiological perspective of the first case of Artesunate treatment failure in an Omani citizen admitted to a hospital in Muscat who originally contracted P. falciparum malaria during travel to Dar Es Salaam, Tanzania.

Citation

Subudhi, A. K., Bienvenu, A.-L., Bonnot, G., Abu-Shamma, R., Khamis, F., Lawati, H. A. A. A., Picot, S., Petersen, E., & Pain, A. (2022). The first case of artemisinin treatment failure of plasmodium falciparum imported to Oman from Tanzania. Journal of Travel Medicine. https://doi.org/10.1093/jtm/taac092

Sponsors

The project was supported by a faculty baseline fund (BAS/1/1020-01-01) from the King Abdullah University of Science and Technology (KAUST) to AP. The authors thank the staff of the Bioscience Core Laboratory in KAUST for FACS assays and Fathia Ben Rached and Zenaida Stead for helping with the ring-stage survival assays. The P. falciparum NF54 strain used in this study was a kind gift from Frederic Ariey from INSERM 1016, Institut Cochin, Paris, France. We also acknowledge Dr. Mohammed Almohammadi, Dr. Farzal Anwar, Abdullah Mohammed Algarni, and Sahal Alawi Jamalallail from the blood transfusion center associated with King Abdullah International Medical Research Center (KAIMRC) for supplying us RBCs to support malaria culture work.