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dc.contributor.authorXiao, Ting Ting
dc.contributor.authorKirschner, Gwendolyn Kristin
dc.contributor.authorKountche, Boubacar Amadou
dc.contributor.authorJamil, Muhammad
dc.contributor.authorMaria, Savina
dc.contributor.authorLube, Vinicius
dc.contributor.authorMironova, Victoria
dc.contributor.authorAl-Babili, Salim
dc.contributor.authorBlilou, Ikram
dc.date.accessioned2022-05-12T06:52:14Z
dc.date.available2022-05-12T06:52:14Z
dc.date.issued2022-05-11
dc.identifier.citationXiao, T. T., Kirschner, G. K., Kountche, B. A., Jamil, M., Maria, S., Lube, V., Mironova, V., al Babili, S., & Blilou, I. (2022). A PLETHORA/PIN-FORMED/auxin network mediates prehaustorium formation in the parasitic plant Striga hermonthica. Plant Physiology. https://doi.org/10.1093/plphys/kiac215
dc.identifier.issn1532-2548
dc.identifier.pmid35543497
dc.identifier.doi10.1093/plphys/kiac215
dc.identifier.urihttp://hdl.handle.net/10754/676861
dc.description.abstractThe parasitic plant Striga (Striga hermonthica) invades the host root through the formation of a haustorium and has detrimental impacts on cereal crops. The haustorium results from the prehaustorium, which is derived directly from the differentiation of the Striga radicle. The molecular mechanisms leading to radicle differentiation shortly after germination remain unclear. In this study, we determined the developmental programs that regulate terminal prehaustorium formation in S. hermonthica at cellular resolution. We showed that shortly after germination, cells in the root meristem undergo multiplanar divisions. During growth, the meristematic activity declines and associates with reduced expression of the stem cell regulator PLETHORA1 and the cell cycle genes CYCLINB1 and HISTONE H4. We also observed a basal localization of the PIN-FORMED (PIN) proteins and a decrease in auxin levels in the meristem. Using the structural layout of the root meristem and the polarity of outer-membrane PIN proteins, we constructed a mathematical model of auxin transport that explains the auxin distribution patterns observed during S. hermonthica root growth. Our results reveal a fundamental molecular and cellular framework governing the switch of S. hermonthica roots to form the invasive prehaustoria.
dc.description.sponsorshipSupported by King Abdullah University of Science and Technology (KAUST) baseline funding given to Ikram Blilou and by the Bill and Melinda Gates Foundation grant OPP1194472 given to Salim Al-Babili. Victoria Mirnova was supported by the Russian Science Foundation 18-74-10008. Savina Maria was supported by 0259-2019-0008-C-01.
dc.description.sponsorshipWe thank Prof. Jiri Friml for generously providing AtPIN1 and AtPIN2 antibodies. We thank Dr. Wei Xu for the technical support during confocal imaging.
dc.publisherOxford University Press (OUP)
dc.relation.urlhttps://academic.oup.com/plphys/advance-article/doi/10.1093/plphys/kiac215/6584021
dc.rightsArchived with thanks to Plant Physiology under a Creative Commons license, details at: https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectroot meristem
dc.subjectRoot differentiation
dc.subjectmathematical model
dc.subjectauxin
dc.subjectPin Proteins
dc.subjectStriga Hermonthica
dc.subjectPrehaustorium
dc.titleA PLETHORA/PIN-FORMED/auxin network mediates prehaustorium formation in the parasitic plant Striga hermonthica
dc.typeArticle
dc.contributor.departmentBESE Division, Plant Cell and Developmental Biology, King Abdullah University of Science and Technology, Thuwal, Kingdom of Saudi Arabia
dc.contributor.departmentBESE Division, The BioActives Lab, King Abdullah University of Science and Technology, Thuwal, Kingdom of Saudi Arabia
dc.contributor.departmentBiological and Environmental Science and Engineering (BESE) Division
dc.contributor.departmentPlant Science
dc.contributor.departmentCenter for Desert Agriculture
dc.identifier.journalPlant Physiology
dc.eprint.versionPost-print
dc.contributor.institutionInstitute of Cytology and Genetics, Lavrentyeva Avenue 10, Novosibirsk, 630090, Russian Federation
dc.contributor.institutionNovosibirsk State University, 2 Pirogova Street, Novosibirsk, 630090, Russian Federation
dc.contributor.institutionPlant Systems Physiology, Radboud University, Heyendaalseweg 135, 6500 AJ Nijmegen, NL
kaust.personXiao, Ting Ting
kaust.personKirschner, Gwendolyn Kristin
kaust.personKountche, Boubacar Amadou
kaust.personJamil, Muhammad
kaust.personLube, Vinicius
kaust.personAl-Babili, Salim
kaust.personBlilou, Ikram
refterms.dateFOA2022-05-12T06:53:26Z
kaust.acknowledged.supportUnitBaseline funding


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Archived with thanks to Plant Physiology under a Creative Commons license, details at: https://creativecommons.org/licenses/by-nc-nd/4.0/
Except where otherwise noted, this item's license is described as Archived with thanks to Plant Physiology under a Creative Commons license, details at: https://creativecommons.org/licenses/by-nc-nd/4.0/