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    Fluorescent ABC-Triblock Polymer Nanocarrier for Cisplatin Delivery to Cancer Cells.

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    Type
    Article
    Authors
    Kulkarni, Bhagyashree cc
    Malhotra, Mehak
    Jayakannan, Manickam cc
    KAUST Department
    KAUST Catalysis Center (KCC)
    Physical Science and Engineering (PSE) Division
    Date
    2022-01-10
    Embargo End Date
    2023-01-10
    Submitted Date
    2021-11-30
    Permanent link to this record
    http://hdl.handle.net/10754/675259
    
    Metadata
    Show full item record
    Abstract
    Monitoring intracellular administration of non-luminescent anticancer drugs like cisplatin is a very challenging task in cancer research. Perylenebisimide (PBI) chromophore tagged fluorescent ABC-triblock polycaprolactone (PCL) nanoscaffold was engineered having carboxylic acid blocks for the chemical conjugation of cisplatin at the core and hydrophilic PEG blocks at the periphery. The amphiphilic ABC triblock Pt-prodrug was self-assembled into
    Citation
    Kulkarni, B., Malhotra, M., & Jayakannan, M. (2022). Fluorescent ABC-Triblock Polymer Nanocarrier for Cisplatin Delivery to Cancer Cells. Chemistry – An Asian Journal. doi:10.1002/asia.202101337
    Sponsors
    The authors thank research grant from Science and Engineering Research Board (SERB), Project No. CRG/2019/000496, New Delhi, INDIA. Mehak Malhotra thanks CSIR-SRF for fellowship. IISER Pune microscopy facilities are acknowledged.
    Publisher
    Wiley
    Journal
    Chemistry, an Asian journal
    DOI
    10.1002/asia.202101337
    PubMed ID
    35001550
    Additional Links
    https://onlinelibrary.wiley.com/doi/10.1002/asia.202101337
    ae974a485f413a2113503eed53cd6c53
    10.1002/asia.202101337
    Scopus Count
    Collections
    Articles; Physical Science and Engineering (PSE) Division; KAUST Catalysis Center (KCC)

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