• Login
    View Item 
    •   Home
    • Theses and Dissertations
    • MS Theses
    • View Item
    •   Home
    • Theses and Dissertations
    • MS Theses
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of KAUSTCommunitiesIssue DateSubmit DateThis CollectionIssue DateSubmit Date

    My Account

    Login

    Quick Links

    Open Access PolicyORCID LibguideTheses and Dissertations LibguideSubmit an Item

    Statistics

    Display statistics

    Characterizing the chemical contaminants diversity and toxic potential of untreated hospital wastewater

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    Baasher.Fras.Master's thesis py (3).pdf
    Size:
    832.9Kb
    Format:
    PDF
    Description:
    Fras Basheer Thesis
    Download
    Type
    Thesis
    Authors
    Baasher, Fras cc
    Advisors
    Hong, Pei-Ying cc
    Committee members
    Saikaly, Pascal cc
    Mahfouz, Magdy M. cc
    Program
    Bioengineering
    KAUST Department
    Biological and Environmental Science and Engineering (BESE) Division
    Date
    2021-12
    Permanent link to this record
    http://hdl.handle.net/10754/673884
    
    Metadata
    Show full item record
    Abstract
    This study characterizes 21 wastewater samples collected from Al-Amal hospital between the period of 12 April till 8 July 2020. Al Almal is a hospital that provides drug addiction and psychological treatment to patients. Using solid-phase extraction and liquid chromatography with tandem mass spectrometry (LC-MS/MS), chemical contaminants profiles in these wastewater samples were determined in a non-targeted manner. These chemicals were then individually analyzed in an in-silico manner by checking against databases and literature to determine if they were mutagenic. By determining the proportion of mutagenic chemicals against the non-mutagenic ones, we aim to determine if untreated hospital wastewater may potentially negatively impact the downstream municipal biological wastewater treatment process. It was determined that 64% of the identified chemicals were not tested for their mutagenic effect, and hence no prior information is available in the literature and databases. Instead, we further performed in-vitro mutagenicity tests using Ames test to determine if the wastewater sample, with all of its chemical constituents, would be mutagenic. Ames test results showed that majority of the samples were non-mutagenic except for 1 sample that imposed a mutagenic effect on Salmonella enterica serovar Typhimurium TA98 and 3 samples with mutagenic effect on TA100. In addition, 1 sample showed a toxic effect on TA100. However, in all 5 instances, these samples only imposed a mutagenic and toxic effect at high concentrations of > 10x. The findings in this study suggest that a specialty hospital like Al Amal does not contribute substantially to mutagenic wastewater streams to the municipal sewer, and hence unlikely to significantly perturb the downstream biological treatment processes. However, there may still be a need to consider ad-hoc contributions of mutagenic and/or toxic wastewater streams from the hospitals.
    Citation
    Baasher, F. (2021). Characterizing the chemical contaminants diversity and toxic potential of untreated hospital wastewater. KAUST Research Repository. https://doi.org/10.25781/KAUST-7I01G
    DOI
    10.25781/KAUST-7I01G
    ae974a485f413a2113503eed53cd6c53
    10.25781/KAUST-7I01G
    Scopus Count
    Collections
    Bioengineering Program; Biological and Environmental Science and Engineering (BESE) Division; MS Theses

    entitlement

     
    DSpace software copyright © 2002-2023  DuraSpace
    Quick Guide | Contact Us | KAUST University Library
    Open Repository is a service hosted by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items. For anonymous users the allowed maximum amount is 50 search results.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.