Exploring the Structure and Performance of Cd–Chalcogenide Photocatalysts in Selective Trifluoromethylation
Taksande, Mayur Rahul
KAUST DepartmentChemical Science Program
KAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
KAUST Grant NumberURF/1/4025
Embargo End Date2022-11-24
Permanent link to this recordhttp://hdl.handle.net/10754/673772
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AbstractThe field of heterogeneous photoredox catalysis has grown substantially and impacted organic synthesis because of the affordability and reusability of catalysts. This study reports radical trifluoromethylation with Cd–chalcogenide semiconductors. Cd semiconductors, particularly CdSe, are readily available, commercial, visible-light-responsive, heterogeneous photocatalysts. The potential of readily available Cd semiconductors, particularly CdSe, is confirmed by their increased photocatalytic activity toward trifluoromethylation with various substrates, such as (hetero)arenes and vinylic amides/acids, via addition, cyclization, and decarboxylation under visible light. The economic significance of this strategy is also highlighted through the scalable synthesis of biologically active molecules followed by catalyst reuse. Moreover, these catalysts are relatively inexpensive compared with transition metal-based homogeneous photocatalysts, presently used in organic synthesis.
CitationMuralirajan, K., Kancherla, R., Bau, J. A., Taksande, M. R., Qureshi, M., Takanabe, K., & Rueping, M. (2021). Exploring the Structure and Performance of Cd–Chalcogenide Photocatalysts in Selective Trifluoromethylation. ACS Catalysis, 14772–14780. doi:10.1021/acscatal.1c04053
SponsorsThis work was financially supported by the King Abdullah University of Science and Technology (KAUST), Saudi Arabia, Office of Sponsored Research (URF/1/4025).
PublisherAmerican Chemical Society (ACS)