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    Organic Bioelectronic Devices for Metabolite Sensing

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    Name:
    acs.chemrev.1c00395.pdf
    Size:
    47.19Mb
    Format:
    PDF
    Description:
    Accepted manuscript
    Embargo End Date:
    2022-10-05
    Download
    Type
    Article
    Authors
    Koklu, Anil cc
    Ohayon, David cc
    Wustoni, Shofarul cc
    Druet, Victor cc
    Saleh, Abdulelah cc
    Inal, Sahika cc
    KAUST Department
    Biological and Environmental Science and Engineering (BESE) Division
    Bioscience Program
    Bioengineering Program
    Date
    2021-10-05
    Embargo End Date
    2022-10-05
    Submitted Date
    2021-05-05
    Permanent link to this record
    http://hdl.handle.net/10754/672245
    
    Metadata
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    Abstract
    Electrochemical detection of metabolites is essential for early diagnosis and continuous monitoring of a variety of health conditions. This review focuses on organic electronic material-based metabolite sensors and highlights their potential to tackle critical challenges associated with metabolite detection. We provide an overview of the distinct classes of organic electronic materials and biorecognition units used in metabolite sensors, explain the different detection strategies developed to date, and identify the advantages and drawbacks of each technology. We then benchmark state-of-the-art organic electronic metabolite sensors by categorizing them based on their application area (in vitro, body-interfaced, in vivo, and cell-interfaced). Finally, we share our perspective on using organic bioelectronic materials for metabolite sensing and address the current challenges for the devices and progress to come.
    Citation
    Koklu, A., Ohayon, D., Wustoni, S., Druet, V., Saleh, A., & Inal, S. (2021). Organic Bioelectronic Devices for Metabolite Sensing. Chemical Reviews. doi:10.1021/acs.chemrev.1c00395
    Publisher
    American Chemical Society (ACS)
    Journal
    Chemical Reviews
    DOI
    10.1021/acs.chemrev.1c00395
    PubMed ID
    34610244
    Additional Links
    https://pubs.acs.org/doi/10.1021/acs.chemrev.1c00395
    ae974a485f413a2113503eed53cd6c53
    10.1021/acs.chemrev.1c00395
    Scopus Count
    Collections
    Articles; Bioengineering Program; Biological and Environmental Science and Engineering (BESE) Division; Bioscience Program

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