Show simple item record

dc.contributor.authorBonzi, Lucrezia C
dc.contributor.authorMonroe, Alison
dc.contributor.authorLehmann, Robert
dc.contributor.authorBerumen, Michael L.
dc.contributor.authorRavasi, Timothy
dc.contributor.authorSchunter, Celia
dc.date.accessioned2021-09-16T06:41:27Z
dc.date.available2021-09-16T06:41:27Z
dc.date.issued2021-09-13
dc.date.submitted2021-05-24
dc.identifier.citationBonzi, L. C., Monroe, A. A., Lehmann, R., Berumen, M. L., Ravasi, T., & Schunter, C. (2021). The time course of molecular acclimation to seawater in a euryhaline fish. Scientific Reports, 11(1). doi:10.1038/s41598-021-97295-3
dc.identifier.issn2045-2322
dc.identifier.pmid34518569
dc.identifier.doi10.1038/s41598-021-97295-3
dc.identifier.urihttp://hdl.handle.net/10754/671260
dc.description.abstractThe Arabian pupfish, Aphanius dispar, is a euryhaline fish inhabiting both inland nearly-freshwater desert ponds and highly saline Red Sea coastal lagoons of the Arabian Peninsula. Desert ponds and coastal lagoons, located respectively upstream and at the mouths of dry riverbeds ("wadies"), have been found to potentially become connected during periods of intense rainfall, which could allow the fish to migrate between these different habitats. Flash floods would therefore flush Arabian pupfish out to sea, requiring a rapid acclimation to a greater than 40 ppt change in salinity. To investigate the molecular pathways of salinity acclimation during such events, a Red Sea coastal lagoon and a desert pond population were sampled, with the latter exposed to a rapid increase in water salinity. Changes in branchial gene expression were investigated via genome-wide transcriptome measurements over time from 6 h to 21 days. The two natural populations displayed basal differences in genes related to ion transport, osmoregulation and immune system functions. These mechanisms were also differentially regulated in seawater transferred fish, revealing their crucial role in long-term adaptation. Other processes were only transiently activated shortly after the salinity exposure, including cellular stress response mechanisms, such as molecular chaperone synthesis and apoptosis. Tissue remodelling processes were also identified as transient, but took place later in the timeline, suggesting their importance to long-term acclimation as they likely equip the fish with lasting adaptations to their new environment. The alterations in branchial functional pathways displayed by Arabian pupfish in response to salinity increases are diverse. These reveal a large toolkit of molecular processes important for adaptation to hyperosmolarity that allow for successful colonization to a wide variety of different habitats.
dc.description.sponsorshipThis study was supported by the King Abdullah University of Science and Technology (KAUST). The project was completed under ethics permit 15IBEC35_Ravasi from the Institutional Biosafety and BioEthics Committee (IBEC) of KAUST. We thank KAUST Coastal and Marine Resources Core Lab and Jessica L. Norstog for assistance with animal collection and maintenance. We also thank KAUST Bioscience Core Lab for assistance with Illumina library preparation and sequencing.
dc.publisherSpringer Science and Business Media LLC
dc.relation.urlhttps://www.nature.com/articles/s41598-021-97295-3
dc.rightsThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleThe time course of molecular acclimation to seawater in a euryhaline fish.
dc.typeArticle
dc.contributor.departmentRed Sea Research Center, Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia.
dc.contributor.departmentMarine Science Program
dc.contributor.departmentBiological and Environmental Science and Engineering (BESE) Division
dc.contributor.departmentRed Sea Research Center (RSRC)
dc.identifier.journalScientific reports
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionMarine Climate Change Unit, Okinawa Institute of Science and Technology Graduate University, 1919‑1 Tancha, Onna‑son, Okinawa, Japan.
dc.contributor.institutionAustralian Research Council Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, QLD, Australia.
dc.contributor.institutionSwire Institute of Marine Science, School of Biological Sciences, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.
dc.identifier.volume11
dc.identifier.issue1
kaust.personBonzi, Lucrezia C
kaust.personMonroe, Alison Ann
kaust.personLehmann, Robert
kaust.personBerumen, Michael L.
dc.date.accepted2021-08-17
dc.relation.issupplementedbybioproject:PRJNA722804
refterms.dateFOA2021-09-16T06:42:23Z
display.relations<b>Is Supplemented By:</b><br/> <ul><li><i>[Bioproject]</i> <br/> Title: Branchial gene expression in A. dispar exposed to increased salinity over a timeline. Publication Date: 2021-04-19. bioproject: <a href="https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA722804" >PRJNA722804</a> Handle: <a href="http://hdl.handle.net/10754/671323" >10754/671323</a></a></li></ul>
kaust.acknowledged.supportUnitKAUST Bioscience Core Lab
kaust.acknowledged.supportUnitKAUST Coastal and Marine Resources Core Lab
dc.date.published-online2021-09-13
dc.date.published-print2021-12


Files in this item

Thumbnail
Name:
s41598-021-97295-3.pdf
Size:
1.697Mb
Format:
PDF
Description:
Publisher's version

This item appears in the following Collection(s)

Show simple item record

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
Except where otherwise noted, this item's license is described as This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.