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Symbiodium_TIGS-S-21-00217.pdf
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Accepted manuscript
Type
ArticleKAUST Department
Marine Science ProgramRed Sea Research Center (RSRC)
Biological and Environmental Science and Engineering (BESE) Division
Date
2021-09-11Online Publication Date
2021-09-11Print Publication Date
2021-09Embargo End Date
2022-09-11Permanent link to this record
http://hdl.handle.net/10754/671147
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Show full item recordAbstract
Photosynthetic microalgae, from the family Symbiodiniaceae, engage in endosymbioses with marine invertebrates, including stony corals. More generally, dinoflagellates are ubiquitous protists and the main primary producers in the oceans. Despite their ecological and economic importance, their biology remains enigmatic. Here we assembled 94 chromosome-scale scaffolds of the ancestral Symbiodiniaceae species Symbiodinium microadriaticum. Contrary to the random order of genes typically found in eukaryotic cells, genes are enriched toward the ends of chromosomes in alternating unidirectional blocks that are sometimes enriched for genes of specific biological processes. These gene blocks are coexpressed and separated by structural boundaries where transcription converges. These structural domains, in turn, comprise the transcription-dependent basic building blocks of the chromosomes that fold as linear rods. Such a highly ordered structure linking gene orientation, transcription, and spatial organization of chromosomes is exceptional.Citation
Voolstra, C. R., Aranda, M., Zhan, Y., & Dekker, J. (2021). Symbiodinium microadriaticum (coral microalgal endosymbiont). Trends in Genetics. doi:10.1016/j.tig.2021.08.008Publisher
Elsevier BVJournal
Trends in GeneticsAdditional Links
https://linkinghub.elsevier.com/retrieve/pii/S0168952521002328ae974a485f413a2113503eed53cd6c53
10.1016/j.tig.2021.08.008