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dc.contributor.authorRashid, Reem B.
dc.contributor.authordu, weiyuan
dc.contributor.authorGriggs, Sophie
dc.contributor.authorMaria, Iuliana P.
dc.contributor.authorMcCulloch, Iain
dc.contributor.authorRivnay, Jonathan
dc.date.accessioned2021-09-09T08:49:20Z
dc.date.available2021-09-09T08:49:20Z
dc.date.issued2021-09-08
dc.date.submitted2021-02-16
dc.identifier.citationRashid, R. B., Du, W., Griggs, S., Maria, I. P., McCulloch, I., & Rivnay, J. (2021). Ambipolar inverters based on cofacial vertical organic electrochemical transistor pairs for biosignal amplification. Science Advances, 7(37). doi:10.1126/sciadv.abh1055
dc.identifier.issn2375-2548
dc.identifier.doi10.1126/sciadv.abh1055
dc.identifier.urihttp://hdl.handle.net/10754/671137
dc.description.abstractOn-site signal amplification for bioelectronic sensing is a desirable approach to improving recorded signal quality and to reducing the burden on signal transmission and back-end electronics. While organic electrochemical transistors (OECTs) have been used as local transducers of bioelectronic signals, their current output presents challenges for implementation. OECT-based circuits offer new opportunities for high-performance signal processing. In this work, we introduce an active sensing node based on cofacial vertical OECTs forming an ambipolar complementary inverter. The inverter, which shows a voltage gain of 28, is composed of two OECTs on opposite side walls of a single active area, resulting in a footprint identical to a planar OECT. The inverter is used as an analog voltage preamplifier for recording electrocardiogram signals when biased at the input voltage corresponding to peak gain. We further demonstrate compatibility with nontraditional fabrication methods with potential benefits for rapid prototyping and large-area printed electronics.
dc.description.sponsorshipWe acknowledge financial support from King Abdullah University of Science and Technology Office of Sponsored Research (OSR) under awards nos. OSR-2018-CARF/CCF-3079 and OSR- 2019-CRG8-4086. This work used Northwestern University Micro/Nano Fabrication Facility (NUFAB), which is partially supported by Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF ECCS-1542205), the Materials Research Science and Engineering Centers (MRSEC; DMR-1720139), the State of Illinois, and Northwestern University. This work made use of the Keck-II and EPIC facilities of Northwestern University’s NUANCE Center, which has received support from the SHyNE Resource (NSF ECCS-1542205); the MRSEC program (NSF DMR-1720139) at the Materials Research Center; the International Institute for Nanotechnology (IIN); the Keck Foundation; and the State of Illinois, through the IIN
dc.publisherAmerican Association for the Advancement of Science (AAAS)
dc.relation.urlhttps://www.science.org/doi/10.1126/sciadv.abh1055
dc.rightsThe Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S.Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleAmbipolar inverters based on cofacial vertical organic electrochemical transistor pairs for biosignal amplification
dc.typeArticle
dc.contributor.departmentKAUST Solar Center (KSC)
dc.contributor.departmentPhysical Science and Engineering (PSE) Division
dc.contributor.departmentChemical Science Program
dc.identifier.journalScience Advances
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionDepartment of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.
dc.contributor.institutionSimpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
dc.contributor.institutionDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford OX1 3TA, UK.
dc.identifier.volume7
dc.identifier.issue37
kaust.personDu, Weiyuan
kaust.personMcCulloch, Iain
kaust.grant.numberOSR-2018-CARF/CCF-3079
kaust.grant.numberOSR- 2019-CRG8-4086
dc.date.accepted2021-07-20
refterms.dateFOA2021-09-09T08:51:24Z
kaust.acknowledged.supportUnitOSR
dc.date.published-online2021-09-08
dc.date.published-print2021-09-10


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The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S.Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).
Except where otherwise noted, this item's license is described as The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S.Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).