Real-time concentration monitoring in microfluidic system via plasmonic nanocrescent arrays
KAUST DepartmentNano Science and Technology Program and KAUST-HKUST Micro/Nanofluidic Joint Laboratory, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
Permanent link to this recordhttp://hdl.handle.net/10754/670029
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AbstractIn this work, on-chip bio/chemical sensor was reported based on localized surface plasmon resonance of nanocrescent patterns fabricated via electron beam lithography. The nanocrescent arrays with different dimensional features exhibited controllable plasmonic properties in accordance with the simulation results based on the finite-difference time-domain model. The highest refractive index sensitivity of the fabricated samples was achieved to be ~699.2. nm/RIU with a figure of merit of ~3.1 when the two opposite crescents own a gap of ~43.3. nm. Such obtained plasmonic sensor was further integrated into the microfluidic system which can simply control the specific analyte concentrations via tuning the flow rate ratios between two injecting microstreams. Our method has successfully demonstrated the capability of the nanocrescent patterns as on-chip plasmonic bio/chemical sensor for real-time monitoring of dynamic concentrations in the microchannel.
CitationZhou, B., Xiao, X., Liu, T., Gao, Y., Huang, Y., & Wen, W. (2016). Real-time concentration monitoring in microfluidic system via plasmonic nanocrescent arrays. Biosensors and Bioelectronics, 77, 385–392. doi:10.1016/j.bios.2015.09.054
SponsorsThe authors would like to acknowledge the support by Hong Kong RGC Grants HKUST 605411 and AOE/P-02/12 PG. The work was also partially supported by the Special Fund for Agro-scientific Research in the Public Interest, Ministry of Agriculture of the People's Republic of China No. 201303045. We would like to thank F. Qin and Prof. J.F. Wang from CUHK for the fruitful discussion.
JournalBIOSENSORS & BIOELECTRONICS
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