Intramolecular Electrochemical Oxybromination of Olefins for the Synthesis of Isoxazolines in Batch and Continuous Flow
KAUST DepartmentKAUST Catalysis Center (KCC) I King Abdullah University of Science and Technology (KAUST) Thuwal 23955-6900 Saudi Arabia
KAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Chemical Science Program
Embargo End Date2022-06-23
Permanent link to this recordhttp://hdl.handle.net/10754/669774
MetadataShow full item record
AbstractA new electrochemical method for the synthesis of 2-isoxazolines is reported. The reaction operates under atmospheric conditions and tolerates air and moisture. The use of potassium bromide as both electrolyte and bromine source precludes the need for toxic, air-sensitive inorganic oxidants or transition metal catalysts.
CitationPrabhakar Kale, A., Nikolaienko, P., Smirnova, K., & Rueping, M. (2021). Intramolecular Electrochemical Oxybromination of Olefins for the Synthesis of Isoxazolines in Batch and Continuous Flow. European Journal of Organic Chemistry, 2021(24), 3496–3500. doi:10.1002/ejoc.202100640
SponsorsThis work was financially supported by the King Abdullah University of Science and Technology (KAUST), Saudi Arabia.