Nanoporous polyethersulfone membranes prepared by mixed solvent phase separation method for protein separation
dc.contributor.author | Li, Peipei | |
dc.contributor.author | Thankamony, Roshni | |
dc.contributor.author | Li, Xiang | |
dc.contributor.author | Li, Zhen | |
dc.contributor.author | Liu, Xiaowei | |
dc.contributor.author | Lai, Zhiping | |
dc.date.accessioned | 2021-06-09T08:34:45Z | |
dc.date.available | 2021-06-09T08:34:45Z | |
dc.date.issued | 2021-06-08 | |
dc.date.submitted | 2020-12-27 | |
dc.identifier.citation | Li, P., Thankamony, R. L., Li, X., Li, Z., Liu, X., & Lai, Z. (2021). Nanoporous polyethersulfone membranes prepared by mixed solvent phase separation method for protein separation. Journal of Membrane Science, 119507. doi:10.1016/j.memsci.2021.119507 | |
dc.identifier.issn | 0376-7388 | |
dc.identifier.doi | 10.1016/j.memsci.2021.119507 | |
dc.identifier.uri | http://hdl.handle.net/10754/669484 | |
dc.description.abstract | Nanoporous polyethersulfone (PES) membranes with high surface porosity and uniform pore size distribution were prepared by combining the phase separation in NMP/nonane mixed solvent system with the traditional nonsolvent induced phase inversion process. The effects of PES concentration, nonane concentration, evaporation time, casting solution temperature, and varied mixed solvent systems on the porous PES membrane surface morphology were thoroughly investigated and optimized. The optimized nanoporous PES membrane showed a high surface porosity with a uniform pore size of 20 nm, rendering an exceptional molecular weight cut-off of as low as 100 k Dalton. In addition, the membrane exhibited a significant molecular size exclusion with water permeance of 121 LMH bar−1, bovine serum albumin (BSA) protein rejection of 60.1%, and γ-globulin protein rejection of 99.5% at 0.5 bar, respectively, demonstrating the potential of the as-prepared nanoporous PES membrane for application in protein separation. | |
dc.description.sponsorship | The work was supported by the King Abdullah University of Science and Technology, Saudi Arabia, under the competitive research grant URF/1/3769-01. | |
dc.publisher | Elsevier BV | |
dc.relation.url | https://linkinghub.elsevier.com/retrieve/pii/S0376738821004555 | |
dc.rights | NOTICE: this is the author’s version of a work that was accepted for publication in Journal of Membrane Science. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Membrane Science, [, , (2021-06-08)] DOI: 10.1016/j.memsci.2021.119507 . © 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.title | Nanoporous polyethersulfone membranes prepared by mixed solvent phase separation method for protein separation | |
dc.type | Article | |
dc.contributor.department | Advanced Membranes and Porous Materials Research Center | |
dc.contributor.department | Biological and Environmental Science and Engineering (BESE) Division | |
dc.contributor.department | Chemical Engineering Program | |
dc.contributor.department | Physical Science and Engineering (PSE) Division | |
dc.identifier.journal | Journal of Membrane Science | |
dc.rights.embargodate | 2023-06-08 | |
dc.eprint.version | Post-print | |
dc.identifier.pages | 119507 | |
kaust.person | Li, Peipei | |
kaust.person | Thankamony, Roshni | |
kaust.person | Li, Xiang | |
kaust.person | Liu, Xiaowei | |
kaust.person | Lai, Zhiping | |
kaust.grant.number | URF/1/3769-01. | |
dc.date.accepted | 2021-06-03 | |
refterms.dateFOA | 2021-06-09T08:35:26Z | |
kaust.acknowledged.supportUnit | competitive research grant | |
dc.date.published-online | 2021-06-08 | |
dc.date.published-print | 2021-06 |
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