Versatile control of the CDC48 segregase by the plant UBX-containing (PUX) proteins
dc.contributor.author | Zhang, Junrui | |
dc.contributor.author | Vancea, Alexandra | |
dc.contributor.author | Shahul Hameed, Umar F. | |
dc.contributor.author | Arold, Stefan T. | |
dc.date.accessioned | 2021-06-08T05:59:46Z | |
dc.date.available | 2021-06-08T05:59:46Z | |
dc.date.issued | 2021-05-14 | |
dc.date.submitted | 2021-03-16 | |
dc.identifier.citation | Zhang, J., Vancea, A. I., Shahul Hameed, U. F., & Arold, S. T. (2021). Versatile control of the CDC48 segregase by the plant UBX-containing (PUX) proteins. Computational and Structural Biotechnology Journal, 19, 3125–3132. doi:10.1016/j.csbj.2021.05.025 | |
dc.identifier.issn | 2001-0370 | |
dc.identifier.doi | 10.1016/j.csbj.2021.05.025 | |
dc.identifier.uri | http://hdl.handle.net/10754/669443 | |
dc.description.abstract | In plants, AAA-adenosine triphosphatase (ATPase) Cell Division Control Protein 48 (CDC48) uses the force generated through ATP hydrolysis to pull, extract, and unfold ubiquitylated or sumoylated proteins from the membrane, chromatin, or protein complexes. The resulting changes in protein or RNA content are an important means for plants to control protein homeostasis and thereby adapt to shifting environmental conditions. The activity and targeting of CDC48 are controlled by adaptor proteins, of which the plant ubiquitin regulatory X (UBX) domain-containing (PUX) proteins constitute the largest family. Emerging knowledge on the structure and function of PUX proteins highlights that these proteins are versatile factors for plant homeostasis and adaptation that might inspire biotechnological applications. | |
dc.description.sponsorship | This research was supported by the King Abdullah University of Science and Technology (KAUST) through the baseline fund and the Award No. URF/1/4039-01 from the Office of Sponsored Research (OSR). We thank I. Blilou for comments on the manuscript. | |
dc.publisher | Elsevier BV | |
dc.relation.url | https://linkinghub.elsevier.com/retrieve/pii/S2001037021002063 | |
dc.rights | This is an open access article under the CC BY license. | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.title | Versatile control of the CDC48 segregase by the plant UBX-containing (PUX) proteins | |
dc.type | Article | |
dc.contributor.department | Biological and Environmental Science and Engineering (BESE) Division | |
dc.contributor.department | Bioscience | |
dc.contributor.department | Bioscience Program | |
dc.contributor.department | Computational Bioscience Research Center (CBRC) | |
dc.contributor.department | Environmental Science and Engineering Program | |
dc.contributor.department | King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center (CBRC), Biological and Environmental Science and Engineering (BESE), Thuwal 23955-6900, Saudi Arabia | |
dc.contributor.department | Structural Biology and Engineering | |
dc.identifier.journal | Computational and Structural Biotechnology Journal | |
dc.eprint.version | Publisher's Version/PDF | |
dc.contributor.institution | Centre de Biochimie Structurale, CNRS, INSERM, Université de Montpellier, 34090 Montpellier, France | |
dc.identifier.volume | 19 | |
dc.identifier.pages | 3125-3132 | |
kaust.person | Zhang, Junrui | |
kaust.person | Vancea, Alexandra-Ioana | |
kaust.person | Shahul Hameed, Umar F. | |
kaust.person | Arold, Stefan T. | |
kaust.grant.number | URF/1/4039-01 | |
dc.date.accepted | 2021-05-13 | |
dc.identifier.eid | 2-s2.0-85107058267 | |
refterms.dateFOA | 2021-06-08T06:01:24Z | |
kaust.acknowledged.supportUnit | Office of Sponsored Research (OSR) | |
dc.date.published-online | 2021-05-14 | |
dc.date.published-print | 2021 |
Files in this item
This item appears in the following Collection(s)
-
Articles
-
Biological and Environmental Science and Engineering (BESE) Division
For more information visit: https://bese.kaust.edu.sa/ -
Bioscience Program
For more information visit: https://bese.kaust.edu.sa/study/Pages/Bioscience.aspx -
Environmental Science and Engineering Program
For more information visit: https://bese.kaust.edu.sa/study/Pages/EnSE.aspx -
Computational Bioscience Research Center (CBRC)