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dc.contributor.authorButt, Haroon
dc.contributor.authorBazin, Jeremie
dc.contributor.authorAlshareef, Sahar
dc.contributor.authorEid, Ayman
dc.contributor.authorBenhamed, Moussa
dc.contributor.authorReddy, Anireddy S. N.
dc.contributor.authorCrespi, Martin
dc.contributor.authorMahfouz, Magdy M.
dc.date.accessioned2021-05-23T08:39:40Z
dc.date.available2021-05-23T08:39:40Z
dc.date.issued2020-05-31
dc.identifier.urihttp://hdl.handle.net/10754/669199
dc.description.abstractThe SF3B complex, a multiprotein component of the U2 snRNP of the spliceosome, mediates branch point selection and facilitates spliceosome assembly and activation. Several splicing modulators bind the SF3B1 and PHF5A subunits of the SF3B complex and globally inhibit splicing. Engineered mutant variants of SF3B1 and PHF5A conferred tolerance to splicing inhibitors with only minor effects on gene expression and AS.
dc.publisherNCBI
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA636200
dc.titleOverlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation
dc.typeBioproject
dc.typeDataset
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Division
dc.contributor.departmentGeneral Materials
dc.contributor.departmentPurchasing
dc.contributor.departmentBioscience Program
dc.contributor.departmentPlant Science
dc.contributor.departmentDesert Agriculture Initiative
dc.contributor.institutionCNRS, INRA, Institute of Plant Sciences Paris-Saclay IPS2, Univ Paris Sud, Univ Evry, Univ Paris-Diderot, Sorbonne Paris-Cite, Universite Paris-Saclay, Orsay, France.
dc.contributor.institutionDepartment of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
kaust.personButt, Haroon
kaust.personAlshareef, Sahar
kaust.personEid, Ayman
kaust.personMahfouz, Magdy M.
dc.relation.issupplementtoDOI:10.1038/s42003-021-02051-y
display.relations<b>Is Supplement To:</b><br/> <ul><li><i>[Article]</i> <br/> Butt, H., Bazin, J., Alshareef, S., Eid, A., Benhamed, M., Reddy, A. S. N., … Mahfouz, M. M. (2021). Overlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation. Communications Biology, 4(1). doi:10.1038/s42003-021-02051-y. DOI: <a href="https://doi.org/10.1038/s42003-021-02051-y" >10.1038/s42003-021-02051-y</a> Handle: <a href="http://hdl.handle.net/10754/669146" >10754/669146</a></a></li></ul>
dc.identifier.bioprojectPRJNA636200


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