SynCells: A 60 × 60 μm2 Electronic Platform with Remote Actuation for Sensing Applications in Constrained Environments
Koman, Volodymyr B.
Strano, Michael S
KAUST Grant NumberCRF2015-SENSORS-2719
Embargo End Date2022-05-07
Permanent link to this recordhttp://hdl.handle.net/10754/669128
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AbstractAutonomous electronic microsystems smaller than the diameter of a human hair (<100 μm) are promising for sensing in confined spaces such as microfluidic channels or the human body. However, they are difficult to implement due to fabrication challenges and limited power budget. Here we present a 60 × 60 μm electronic microsystem platform, or SynCell, that overcomes these issues by leveraging the integration capabilities of two-dimensional material circuits and the low power consumption of passive germanium timers, memory-like chemical sensors, and magnetic pads. In a proof-of-concept experiment, we magnetically positioned SynCells in a microfluidic channel to detect putrescine. After we extracted them from the channel, we successfully read out the timer and sensor signal, the latter of which can be amplified by an onboard transistor circuit. The concepts developed here will be applicable to microsystems targeting a variety of applications from microfluidic sensing to biomedical research.
CitationHempel, M., Schroeder, V., Park, C., Koman, V. B., Xue, M., McVay, E., … Palacios, T. (2021). SynCells: A 60 × 60 μm2 Electronic Platform with Remote Actuation for Sensing Applications in Constrained Environments. ACS Nano. doi:10.1021/acsnano.1c01259
SponsorsThe authors acknowledge financial support from the Air Force Office of Scientific Research under the MURI-FATE programs (Grant Nos. FA9550-15-1-0514 and FA9550-16-1-0031) as well as partial support by the ARO project W911NF-19-10372 (award title: Optical Communication with Synthetic Cells). V.S. was supported by the KAUST sensor project CRF2015-SENSORS-2719. This work was carried out in part using MIT’s Microsystems Technology Laboratories and MIT.nano
PublisherAmerican Chemical Society (ACS)