An Emerging Clone (ST2096) of Klebsiella pneumoniae Clonal Complex 14 With Enhanced Virulence Causes an Outbreak in Saudi Arabia

Hala, Sharif; Antony, C. Paul; Alshehri, M.; Alsaedi, A.; Thaqafi, O.A. Al; Al-Ahmadi, G.; Kaaki, M.; Alazmi, Meshari; Alhaj-Hussein, T.B.; Yasen, M.; Zowawi, M.H.; Al-Amri, A.; Pain, Arnab

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Abstract

Nosocomial infections caused by multidrug-resistant (MDR) Klebsiella pneumoniae strains represent a growing threat that needs to be addressed urgently. The principal pathogenic reservoirs for transmission of Klebsiella are the gastrointestinal tract and healthcare workers’ hands where the organism can spread rapidly leading often to a nosocomial outbreak. Therefore, the identification and management of such infections are indispensable. Whole-genome sequencing (WGS) could serve as an efficient tool allowing to track resistant, virulence factors as well as identify the phylogenetic pattern. Here, we aimed to apply such a method to understand the reason behind the spread of K. pneumoniae in hospital.

Citation

Hala, S., Antony, C. P., Alshehri, M., Alsaedi, A., Thaqafi, O. A. A., Al-Ahmadi, G., … Pain, A. (2020). An Emerging Clone (ST2096) of Klebsiella pneumoniae Clonal Complex 14 With Enhanced Virulence Causes an Outbreak in Saudi Arabia. Journal of Infection and Public Health, 13(2), 363–364. doi:10.1016/j.jiph.2020.01.156

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