Emergence of mobile colistin resistance genes mcr-1 and mcr-8 in Saudi Arabia

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Type
Presentation
Authors
Hala, Sharif cc
Paul Antony, C
Alshehri, M
Alsaedi, A
O.Al Thaqafi, A
Momin, A A
Kaaki, M
Alhaj-Hussein, B T
Zowawi, H M
Al-Amri, A
Pain, Arnab cc
KAUST Department
Biological and Environmental Sciences and Engineering (BESE) Division
Bioscience Program
King Abdullah University Of Science And Technology.
Pathogen Genomics Laboratory
Date
2020-02
Permanent link to this record
http://hdl.handle.net/10754/667642

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Abstract
Colistin represents the last-resort antibiotics used for treating carbapenem-resistant Enterobacteriaceae related infections. Colistin resistance has been reported in Saudi Arabia in Gram-negative bacteria (up to 40%). Nevertheless, only a handful of cases were identified to be mcr-linked due to the current clinical microbiology techniques, which do not utilize Whole-Genome Sequencing (WGS). In this study, we surveyed mcrtypes from Multiple-Drug resistant (MDR) Klebsiella pnumoniea clinical isolate using WGS.
Citation
Hala, S., Paul Antony, C., Alshehri, M., Alsaedi, A., O.Al Thaqafi, A., Momin, A. A., … Pain, A. (2020). Emergence of mobile colistin resistance genes mcr-1 and mcr-8 in Saudi Arabia. Journal of Infection and Public Health, 13(2), 329. doi:10.1016/j.jiph.2020.01.064
Publisher
Elsevier BV
Journal
Journal of Infection and Public Health
DOI
10.1016/j.jiph.2020.01.064
Additional Links
https://linkinghub.elsevier.com/retrieve/pii/S1876034120300654
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Biological and Environmental Science and Engineering (BESE) Division; Bioscience Program; Presentations
This article is available under the Creative Commons CC-BY-NC-ND license and permits non-commercial use of the work as published, without adaptation or alteration provided the work is fully attributed.
Except where otherwise noted, this item's license is described as This article is available under the Creative Commons CC-BY-NC-ND license and permits non-commercial use of the work as published, without adaptation or alteration provided the work is fully attributed.