Block Copolymer-Based Magnetic Mixed Matrix Membranes—Effect of Magnetic Field on Protein Permeation and Membrane Fouling
Type
ArticleAuthors
Upadhyaya, Lakshmeesha
Semsarilar, Mona

Quemener, Damien

Fernández-Pacheco, Rodrigo
Martinez, Gema
Coelhoso, Isabel M.

Nunes, Suzana Pereira

Crespo, João G.
Mallada, Reyes

Portugal, Carla A. M.
KAUST Department
Biological and Environmental Science and Engineering (BESE) DivisionEnvironmental Science and Engineering Program
Nanostructured Polymeric Membrane Lab
Date
2021-02-02Submitted Date
2020-12-30Permanent link to this record
http://hdl.handle.net/10754/667300
Metadata
Show full item recordAbstract
In this study, we report the impact of the magnetic field on protein permeability through magnetic-responsive, block copolymer, nanocomposite membranes with hydrophilic and hydrophobic characters. The hydrophilic nanocomposite membranes were composed of spherical polymeric nanoparticles (NPs) synthesized through polymerization-induced self-assembly (PISA) with iron oxide NPs coated with quaternized poly(2-dimethylamino)ethyl methacrylate. The hydrophobic nanocomposite membranes were prepared via nonsolvent-induced phase separation (NIPS) containing poly (methacrylic acid) and meso-2,3-dimercaptosuccinic acid-coated superparamagnetic nanoparticles (SPNPs). The permeation experiments were carried out using bovine serum albumin (BSA) as the model solute, in the absence of the magnetic field and under permanent and cyclic magnetic field conditions OFF/ON (strategy 1) and ON/OFF (strategy 2). It was observed that the magnetic field led to a lower reduction in the permeate fluxes of magnetic-responsive membranes during BSA permeation, regardless of the magnetic field strategy used, than that obtained in the absence of the magnetic field. Nevertheless, a comparative analysis of the effect caused by the two cyclic magnetic field strategies showed that strategy 2 allowed for a lower reduction of the original permeate fluxes during BSA permeation and higher protein sieving coefficients. Overall, these novel magneto-responsive block copolymer nanocomposite membranes proved to be competent in mitigating biofouling phenomena in bioseparation processes.Citation
Upadhyaya, L., Semsarilar, M., Quemener, D., Fernández-Pacheco, R., Martinez, G., Coelhoso, I. M., … Portugal, C. A. M. (2021). Block Copolymer-Based Magnetic Mixed Matrix Membranes—Effect of Magnetic Field on Protein Permeation and Membrane Fouling. Membranes, 11(2), 105. doi:10.3390/membranes11020105Sponsors
Lakshmeesha Upadhyaya acknowledges the doctorate completed at the Institut Européen des Membranes and carried out in three universities: Université de Montpellier (France), Universidad de Zaragoza (Spain) and Universidade Nova de Lisboa (Portugal) and supported by European Commission—Education, Audiovisual and Culture Executive Agency (EACEA), under the program: Erasmus Mundus Doctorate in Membrane Engineering—EUDIME (FPA N◦ 2011–0014, Edition III, http:/eudime.unical.it). CIBER-BBN (initiative funded by the VI National R&D&i Plan 2008– 2011), Iniciativa Ingenio 2010, Consolider Program, is gratefully acknowledged. The synthesis of the inorganic nanomaterials has been performed by the Synthesis of Nanoparticles Unit of the ICTS “NANBIOSIS” at the Institute of Nanoscience of Aragon (INA)-Universidad de Zaragoza.Publisher
MDPI AGJournal
MembranesPubMed ID
33540798Additional Links
https://www.mdpi.com/2077-0375/11/2/105ae974a485f413a2113503eed53cd6c53
10.3390/membranes11020105
Scopus Count
Except where otherwise noted, this item's license is described as This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
Related articles
- Poly(Lactic Acid) Hemodialysis Membranes with Poly(Lactic Acid)-block-Poly(2-Hydroxyethyl Methacrylate) Copolymer As Additive: Preparation, Characterization, and Performance.
- Authors: Zhu L, Liu F, Yu X, Xue L
- Issue date: 2015 Aug 19
- Influence of Magnetic Nanoparticles on PISA Preparation of Poly(Methacrylic Acid)-b-Poly(Methylmethacrylate) Nano-Objects.
- Authors: Upadhyaya L, Egbosimba C, Qian X, Wickramasinghe R, Fernández-Pacheco R, Coelhoso IM, Portugal CAM, Crespo JG, Quemener D, Semsarilar M
- Issue date: 2019 Jan
- Magnetoresponsive Poly(ether sulfone)-Based Iron Oxide cum Hydrogel Mixed Matrix Composite Membranes for Switchable Molecular Sieving.
- Authors: Lin X, Nguyen Quoc B, Ulbricht M
- Issue date: 2016 Oct 26
- Biofouling resistance of ultrafiltration membranes controlled by surface self-assembled coating with PEGylated copolymers.
- Authors: Chiag YC, Chang Y, Chen WY, Ruaan RC
- Issue date: 2012 Jan 17
- Highly hydrophilic polyvinylidene fluoride (PVDF) ultrafiltration membranes via postfabrication grafting of surface-tailored silica nanoparticles.
- Authors: Liang S, Kang Y, Tiraferri A, Giannelis EP, Huang X, Elimelech M
- Issue date: 2013 Jul 24