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dc.contributor.authorBalaban, Simge
dc.contributor.authorBeduk, Tutku
dc.contributor.authorDurmus, Ceren
dc.contributor.authorAydindogan, Eda
dc.contributor.authorSalama, Khaled N.
dc.contributor.authorTimur, Suna
dc.date.accessioned2021-01-20T06:39:04Z
dc.date.available2021-01-20T06:39:04Z
dc.date.issued2021-01-08
dc.date.submitted2020-09-16
dc.identifier.citationBalaban, S., Beduk, T., Durmus, C., Aydindogan, E., Salama, K. N., & Timur, S. (2021). Laser-scribed Graphene Electrodes as an Electrochemical Immunosensing Platform for Cancer Biomarker “eIF3d.” Electroanalysis. doi:10.1002/elan.202060482
dc.identifier.issn1521-4109
dc.identifier.issn1040-0397
dc.identifier.doi10.1002/elan.202060482
dc.identifier.urihttp://hdl.handle.net/10754/666942
dc.description.abstracteIF3d is a protein biomarker which has a potential for the diagnosis of various cancers. Herein, a bio-platform was constructed for eIF3d sensing by using LSG and surface functionalization with anti eIF3d antibody via EDC/NHS chemistry. Following the surface modifications, XPS and several electrochemical methods were used. Difference in the signals were related to biomarker amounts between 75–500 ng/mL. LOD was calculated as 50.4 ng/mL. Selectivity of biosensor was tested by using of various interference molecules. EIF3d was also successfully detected in synthetic biological samples. Thus, to the best of our knowledge, this study is one of the rare studies on use of LSGs in immunosensor studies.
dc.description.sponsorshipThe authors would like to express their acknowledgements to the financial support of funding from King Abdullah University of Science and Technology (KAUST), Saudi Arabia. Biosensing experiments as well as SEM and XPS analysis were conducted in Ege University, Central Research Test and Analysis Laboratory Application and Research Center (EGE-MATAL).
dc.publisherWiley
dc.relation.urlhttps://onlinelibrary.wiley.com/doi/10.1002/elan.202060482
dc.titleLaser-scribed Graphene Electrodes as an Electrochemical Immunosensing Platform for Cancer Biomarker ‘eIF3d’
dc.typeArticle
dc.contributor.departmentMaterial Science and Engineering Program
dc.contributor.departmentPhysical Science and Engineering (PSE) Division
dc.contributor.departmentElectrical Engineering Program
dc.contributor.departmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
dc.identifier.journalElectroanalysis
dc.rights.embargodate2022-01-08
dc.eprint.versionPost-print
dc.contributor.institutionDepartment of Biochemistry, Faculty of Science, Ege University, 35100, Bornova, Izmir, Turkey
dc.contributor.institutionCentral Research Testing and Analysis Laboratory Research and Application Center, Ege University, 35100, Bornova, Izmir, Turkey
kaust.personBeduk, Tutku
kaust.personSalama, Khaled N.
dc.date.accepted2020-12-07
dc.identifier.eid2-s2.0-85099235117
refterms.dateFOA2021-01-20T12:05:58Z


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