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    Electrochemical sensors targeting salivary biomarkers: A comprehensive review

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    Name:
    Electrochemical sensors_electrochemical sensors.pdf
    Size:
    2.816Mb
    Format:
    PDF
    Description:
    Accepted manuscript
    Embargo End Date:
    2022-12-01
    Download
    Type
    Article
    Authors
    Mani, Veerappan cc
    Beduk, Tutku cc
    Khushaim, Walaa cc
    Ceylan, Ayse Elcin cc
    Timur, Suna cc
    Wolfbeis, Otto S. cc
    Salama, Khaled N. cc
    KAUST Department
    Sensors Lab, Advanced Membranes and Porous Materials Center (AMPMC), Computer, Electrical and Mathematical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Saudi Arabia.
    Material Science and Engineering Program
    Physical Science and Engineering (PSE) Division
    Bioscience
    Biological and Environmental Sciences and Engineering (BESE) Division
    Electrical Engineering Program
    Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
    Date
    2020-12
    Embargo End Date
    2022-12-01
    Submitted Date
    2020-10-03
    Permanent link to this record
    http://hdl.handle.net/10754/666821
    
    Metadata
    Show full item record
    Abstract
    The analysis of salivary markers has grown into a promising non-invasive route for easy, safe, and pain-free monitoring and has the potential to alter the existing way of clinical diagnosis and management. Advancements in sensing technology, the arrival of novel materials, the innovative fabrication technologies, and sampling accuracy have made significant progress and establishing saliva as a fluid for routine analysis. Salivary biomarkers are useful to diagnose not only cardiovascular diseases, bacterial or viral infections but also cancer, diabetes, or Alzheimer’s disease. In addition, saliva is analyzed in toxicology, forensic medicine and drug abuse. Electrochemical assays and sensors are well accepted tools because they allow for fast and cost-effective analysis. Nanomaterials, microfluidics, smartphones, paper-based, flexible and wearable devices have made significant advancements in saliva analysis. This review discusses the recent progress made in electrochemical methodologies for detecting salivary biomarkers
    Citation
    Mani, V., Beduk, T., Khushaim, W., Ceylan, A. E., Timur, S., Wolfbeis, O. S., & Salama, K. N. (2020). Electrochemical sensors targeting salivary biomarkers: A comprehensive review. TrAC Trends in Analytical Chemistry, 116164. doi:10.1016/j.trac.2020.116164
    Sponsors
    This work was supported financially by King Abdullah University of Science and Technology (KAUST), Saudi Arabia.
    Publisher
    Elsevier BV
    Journal
    TrAC Trends in Analytical Chemistry
    DOI
    10.1016/j.trac.2020.116164
    Additional Links
    https://linkinghub.elsevier.com/retrieve/pii/S0165993620303939
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.trac.2020.116164
    Scopus Count
    Collections
    Articles; Biological and Environmental Sciences and Engineering (BESE) Division; Physical Science and Engineering (PSE) Division; Electrical Engineering Program; Material Science and Engineering Program; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division

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