Electrochemical sensors targeting salivary biomarkers: A comprehensive review
Ceylan, Ayse Elcin
Wolfbeis, Otto S.
Salama, Khaled N.
KAUST DepartmentSensors Lab, Advanced Membranes and Porous Materials Center (AMPMC), Computer, Electrical and Mathematical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Saudi Arabia.
Material Science and Engineering Program
Physical Science and Engineering (PSE) Division
Biological and Environmental Sciences and Engineering (BESE) Division
Electrical Engineering Program
Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
Embargo End Date2022-12-01
Permanent link to this recordhttp://hdl.handle.net/10754/666821
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AbstractThe analysis of salivary markers has grown into a promising non-invasive route for easy, safe, and pain-free monitoring and has the potential to alter the existing way of clinical diagnosis and management. Advancements in sensing technology, the arrival of novel materials, the innovative fabrication technologies, and sampling accuracy have made significant progress and establishing saliva as a fluid for routine analysis. Salivary biomarkers are useful to diagnose not only cardiovascular diseases, bacterial or viral infections but also cancer, diabetes, or Alzheimer’s disease. In addition, saliva is analyzed in toxicology, forensic medicine and drug abuse. Electrochemical assays and sensors are well accepted tools because they allow for fast and cost-effective analysis. Nanomaterials, microfluidics, smartphones, paper-based, flexible and wearable devices have made significant advancements in saliva analysis. This review discusses the recent progress made in electrochemical methodologies for detecting salivary biomarkers
CitationMani, V., Beduk, T., Khushaim, W., Ceylan, A. E., Timur, S., Wolfbeis, O. S., & Salama, K. N. (2020). Electrochemical sensors targeting salivary biomarkers: A comprehensive review. TrAC Trends in Analytical Chemistry, 116164. doi:10.1016/j.trac.2020.116164
SponsorsThis work was supported financially by King Abdullah University of Science and Technology (KAUST), Saudi Arabia.