Electrochemical sensors targeting salivary biomarkers: A comprehensive review
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Electrochemical sensors_electrochemical sensors.pdf
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Accepted manuscript
Embargo End Date:
2022-12-01
Type
ArticleAuthors
Mani, Veerappan
Beduk, Tutku

Khushaim, Walaa

Ceylan, Ayse Elcin

Timur, Suna

Wolfbeis, Otto S.

Salama, Khaled N.

KAUST Department
Sensors Lab, Advanced Membranes and Porous Materials Center (AMPMC), Computer, Electrical and Mathematical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Saudi Arabia.Material Science and Engineering Program
Physical Science and Engineering (PSE) Division
Bioscience
Biological and Environmental Sciences and Engineering (BESE) Division
Electrical Engineering Program
Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
Date
2020-12Embargo End Date
2022-12-01Submitted Date
2020-10-03Permanent link to this record
http://hdl.handle.net/10754/666821
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Show full item recordAbstract
The analysis of salivary markers has grown into a promising non-invasive route for easy, safe, and pain-free monitoring and has the potential to alter the existing way of clinical diagnosis and management. Advancements in sensing technology, the arrival of novel materials, the innovative fabrication technologies, and sampling accuracy have made significant progress and establishing saliva as a fluid for routine analysis. Salivary biomarkers are useful to diagnose not only cardiovascular diseases, bacterial or viral infections but also cancer, diabetes, or Alzheimer’s disease. In addition, saliva is analyzed in toxicology, forensic medicine and drug abuse. Electrochemical assays and sensors are well accepted tools because they allow for fast and cost-effective analysis. Nanomaterials, microfluidics, smartphones, paper-based, flexible and wearable devices have made significant advancements in saliva analysis. This review discusses the recent progress made in electrochemical methodologies for detecting salivary biomarkersCitation
Mani, V., Beduk, T., Khushaim, W., Ceylan, A. E., Timur, S., Wolfbeis, O. S., & Salama, K. N. (2020). Electrochemical sensors targeting salivary biomarkers: A comprehensive review. TrAC Trends in Analytical Chemistry, 116164. doi:10.1016/j.trac.2020.116164Sponsors
This work was supported financially by King Abdullah University of Science and Technology (KAUST), Saudi Arabia.Publisher
Elsevier BVAdditional Links
https://linkinghub.elsevier.com/retrieve/pii/S0165993620303939ae974a485f413a2113503eed53cd6c53
10.1016/j.trac.2020.116164