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    Carotenoid Biofortification of Crops in the CRISPR Era

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    Type
    Article
    Authors
    Zheng, Xiongjie cc
    Kuijer, Hendrik N.J. cc
    Al-Babili, Salim cc
    KAUST Department
    Biological and Environmental Science and Engineering (BESE) Division
    Center for Desert Agriculture
    Environmental Science and Engineering Program
    King Abdullah University of Science and Technology (KAUST), Division of Biological and Environmental Science and Engineering, Center for Desert Agriculture, the BioActives Laboratory, Thuwal 23955-6900, Saudi Arabia.
    Plant Science
    Date
    2020-12-29
    Online Publication Date
    2020-12-29
    Print Publication Date
    2021-09
    Embargo End Date
    2021-12-29
    Permanent link to this record
    http://hdl.handle.net/10754/666788
    
    Metadata
    Show full item record
    Abstract
    Carotenoids are micronutrients important for human health. The continuous improvements in clustered regularly interspaced short palindromic repeats (CRISPR)-based genome-editing techniques make rapid, DNA/transgene-free and targeted multiplex genetic modification a reality, thus promising to accelerate the breeding and generation of ‘golden’ staple crops. We discuss here the progress and future prospects of CRISPR/Cas9 applications for carotenoid biofortification.
    Citation
    Zheng, X., Kuijer, H. N. J., & Al-Babili, S. (2020). Carotenoid Biofortification of Crops in the CRISPR Era. Trends in Biotechnology. doi:10.1016/j.tibtech.2020.12.003
    Sponsors
    We thank Dr Jianing Mi for valuable discussions and want to apologize to colleagues whose work could not be discussed and cited here due to space limitations. No conflict of interest declared. This work was supported by baseline funding from King Abdullah University of Science and Technology (KAUST), Saudi Arabia.
    Publisher
    Elsevier BV
    Journal
    Trends in Biotechnology
    DOI
    10.1016/j.tibtech.2020.12.003
    Additional Links
    https://linkinghub.elsevier.com/retrieve/pii/S0167779920303279
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.tibtech.2020.12.003
    Scopus Count
    Collections
    Articles; Biological and Environmental Science and Engineering (BESE) Division; Environmental Science and Engineering Program; Center for Desert Agriculture

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