Type
ArticleAuthors
Baig, Hasan
Fontanarossa, Pedro

Kulkarni, Vishwesh

McLaughlin, James Alastair

Vaidyanathan, Prashant

Bartley, Bryan

Beal, Jacob

Crowther, Matthew
Gorochowski, Thomas E

Grunberg, Raik

Misirli, Goksel

Scott-Brown, James

Oberortner, Ernst

Wipat, Anil

Myers, Chris J

Date
2020-06-27Submitted Date
2020-04-02Permanent link to this record
http://hdl.handle.net/10754/666298
Metadata
Show full item recordAbstract
Synthetic biology builds upon genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. When designing a synthetic system, synthetic biologists need to exchange information about multiple types of molecules, the intended behavior of the system, and actual experimental measurements. The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, following an open community process involving both wet bench scientists and dry scientific modelers and software developers, across academia, industry, and other institutions. This document describes SBOL 3.0.0, which condenses and simplifies previous versions of SBOL based on experiences in deployment across a variety of scientific and industrial settings. In particular, SBOL 3.0.0, (1) separates sequence features from part/sub-part relationships, (2) renames Component Definition/Component to Component/Sub-Component, (3) merges Component and Module classes, (4) ensures consistency between data model and ontology terms, (5) extends the means to define and reference Sub-Components, (6) refines requirements on object URIs, (7) enables graph-based serialization, (8) moves Systems Biology Ontology (SBO) for Component types, (9) makes all sequence associations explicit, (10) makes interfaces explicit, (11) generalizes Sequence Constraints into a general structural Constraint class, and (12) expands the set of allowed constraints.Citation
Baig, H., Fontanarrosa, P., Kulkarni, V., McLaughlin, J. A., Vaidyanathan, P., Bartley, B., … Myers, C. J. (2020). Synthetic biology open language (SBOL) version 3.0.0. Journal of Integrative Bioinformatics, 0(0). doi:10.1515/jib-2020-0017Publisher
Walter de Gruyter GmbHPubMed ID
32589605Additional Links
https://www.degruyter.com/view/journals/jib/ahead-of-print/article-10.1515-jib-2020-0017/article-10.1515-jib-2020-0017.xmlae974a485f413a2113503eed53cd6c53
10.1515/jib-2020-0017
Scopus Count
Except where otherwise noted, this item's license is described as This work is made available under the Creative Commons Attribution 4.0 International Public License.
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