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dc.contributor.authorZaidi, Syed Shan-e-Ali
dc.contributor.authorMahas, Ahmed
dc.contributor.authorVanderschuren, Hervé
dc.contributor.authorMahfouz, Magdy M.
dc.date.accessioned2020-12-01T07:27:17Z
dc.date.available2020-12-01T07:27:17Z
dc.date.issued2020-11-30
dc.date.submitted2020-08-25
dc.identifier.citationZaidi, S. S.-A., Mahas, A., Vanderschuren, H., & Mahfouz, M. M. (2020). Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants. Genome Biology, 21(1). doi:10.1186/s13059-020-02204-y
dc.identifier.issn1474-760X
dc.identifier.doi10.1186/s13059-020-02204-y
dc.identifier.urihttp://hdl.handle.net/10754/666173
dc.description.abstractAbstractTo meet increasing global food demand, breeders and scientists aim to improve the yield and quality of major food crops. Plant diseases threaten food security and are expected to increase because of climate change. CRISPR genome-editing technology opens new opportunities to engineer disease resistance traits. With precise genome engineering and transgene-free applications, CRISPR is expected to resolve the major challenges to crop improvement. Here, we discuss the latest developments in CRISPR technologies for engineering resistance to viruses, bacteria, fungi, and pests. We conclude by highlighting current concerns and gaps in technology, as well as outstanding questions for future research.
dc.description.sponsorshipWe wish to thank members of the Laboratory for Genome Engineering and Synthetic Biology at King Abdullah University of Science and Technology for helpful discussions and comments on the manuscript.
dc.description.sponsorshipThis publication is based upon work supported by the King Abdullah University of Science and Technology (KAUST) Office of Sponsored Research (OSR) under Award No. OSR-2015-CRG4-2647. The authors acknowledge financial support from the Belgian FNRS grant M.i.S. F.4515.17 to H.V. and grant 1.B456.20 to S.S.Z. and H.V.
dc.publisherSpringer Nature
dc.relation.urlhttps://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-02204-y
dc.rightsThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleEngineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants
dc.typeArticle
dc.contributor.departmentBioscience Program
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Division
dc.contributor.departmentPlant Science
dc.contributor.departmentDesert Agriculture Initiative
dc.identifier.journalGenome Biology
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionPlant Genetics, TERRA Teaching and Research Center, Gembloux Agro-Bio Tech, University of Liège, Gembloux, Belgium.
dc.contributor.institutionLaboratory of Tropical Crop Improvement, Division of Crop Biotechnics, Biosystems Department, KU Leuven, Leuven, Belgium.
dc.identifier.volume21
dc.identifier.issue1
kaust.personMahas, Ahmed
kaust.personMahfouz, Magdy M.
kaust.grant.numberOSR-2015-CRG4-2647
dc.date.accepted2020-11-13
refterms.dateFOA2020-12-01T07:28:21Z
kaust.acknowledged.supportUnitOSR


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This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
Except where otherwise noted, this item's license is described as This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.