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dc.contributor.authorLimongi, Tania
dc.contributor.authorBrigo, Laura
dc.contributor.authorTirinato, Luca
dc.contributor.authorPagliari, Francesca
dc.contributor.authorGandin, Alessandro
dc.contributor.authorContessotto, Paolo
dc.contributor.authorGiugni, Andrea
dc.contributor.authorBrusatin, Giovanna
dc.date.accessioned2020-11-15T11:08:08Z
dc.date.available2020-11-15T11:08:08Z
dc.date.issued2020-11-13
dc.date.submitted2020-10-30
dc.identifier.citationLimongi, T., Brigo, L., Tirinato, L., Pagliari, F., Gandin, A., Contessotto, P., … Brusatin, G. (2020). Three-dimensionally two-photon lithography realized vascular grafts. Biomedical Materials. doi:10.1088/1748-605x/abca4b
dc.identifier.issn1748-6041
dc.identifier.pmid33186926
dc.identifier.doi10.1088/1748-605x/abca4b
dc.identifier.urihttp://hdl.handle.net/10754/665941
dc.description.abstractGeneration of artifical vascular grafts (TEVG) as blood vessel substitutes is a primary challenge in biomaterial and tissue engineering research. Ideally, these grafts should be able to recapitulate physiological and mechanical properties of natural vessels and guide the assembly of an endothelial cell lining to ensure hemo-compatibility. In this paper, we advance on this challenging task by designing and fabricating 3D vessel analogues by two-photon laser lithography using a synthetic photoresist. These scaffolds guarantee human endothelial cell adhesion and proliferation, and proper elastic behaviour to withstand the pressure exerted by blood flow.
dc.description.sponsorshipG. B. acknowledges the University of Padova for financial support of through "Finanziamento per le attrezzature scientifiche finalizzate alla ricerca - Bando 2013" and SID project “3D Engineered Biopolymers Micro Fabrication by Two-Photon Laser Additive Manufacturing”. A. G. acknowledges financial support from the KAUST funding through CRG5 project OSR award #: OCRF-2016-CRG5.
dc.publisherIOP Publishing
dc.relation.urlhttps://iopscience.iop.org/article/10.1088/1748-605X/abca4b
dc.rightsAs the Version of Record of this article is going to be / has been published on a gold open access basis under a CC BY 3.0 licence, this Accepted Manuscript is available for reuse under a CC BY 3.0 licence immediately. Everyone is permitted to use all or part of the original content in this article, provided that they adhere to all the terms of the licence https://creativecommons.org/licences/by/3.0.
dc.rights.urihttps://creativecommons.org/licences/by/3.0
dc.titleThree-dimensionally two-photon lithography realized vascular grafts.
dc.typeArticle
dc.contributor.departmentPhysical Science and Engineering (PSE) Division
dc.identifier.journalBiomedical materials (Bristol, England)
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionDepartment of Applied Science and Technology, Politecnico di Torino, Torino, Piemonte, ITALY.
dc.contributor.institutionUniversità degli Studi di Padova, Padova, 35122, ITALY.
dc.contributor.institutionDivision of BioMedical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, GERMANY.
dc.contributor.institutionDepartment of Industrial Engineering, University of Padova and INSTM, via Marzolo 9, 35131, Padova, ITALY.
dc.contributor.institutionMedicina Molecolare, Università degli Studi di Padova, Via Bassi 58B, Padova, 35122, ITALY.
dc.contributor.institutionDepartment of Industrial Engineering, Universita degli Studi di Padova, Via Marzolo 9, 35131 Padova, Padova, ITALY.
kaust.personGiugni, Andrea
kaust.grant.numberOCRF-2016-CRG5
dc.date.accepted2020-11-13
refterms.dateFOA2020-11-15T11:09:08Z
kaust.acknowledged.supportUnitOSR


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As the Version of Record of this article is going to be / has been published on a gold open access basis under a CC BY 3.0 licence, this Accepted Manuscript is available for reuse under a CC BY 3.0 licence immediately. Everyone is permitted to use all or part of the original content in this article, provided that they adhere to all the terms of the licence https://creativecommons.org/licences/by/3.0.
Except where otherwise noted, this item's license is described as As the Version of Record of this article is going to be / has been published on a gold open access basis under a CC BY 3.0 licence, this Accepted Manuscript is available for reuse under a CC BY 3.0 licence immediately. Everyone is permitted to use all or part of the original content in this article, provided that they adhere to all the terms of the licence https://creativecommons.org/licences/by/3.0.