Optimal correlation order in superresolution optical fluctuation microscopy
Mikhalychev, A. B.
Karuseichyk, I. L.
Lyakhov, D. A.
Michels, Dominik L.
KAUST DepartmentComputer, Electrical and Mathematical Science and Engineering Division, 4700 King Abdullah University of Science and Technology, Thuwal 23955-6900, Kingdom of Saudi Arabia
Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
Computer Science Program
Visual Computing Center (VCC)
Permanent link to this recordhttp://hdl.handle.net/10754/665447
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AbstractHere, we show that superresolution optical fluctuation microscopy might not lead to ideally infinite superresolution enhancement with increasing of the order of measured cumulants. Using information analysis for estimating error bounds on the determination of point-source positions, we show that reachable precision per measurement might be saturated with increasing of the order of the measured cumulants in the superresolution regime. In fact, there is an optimal correlation order beyond which there is practically no improvement for objects of three and more point sources. However, for objects of just two sources, one still has an intuitively expected resolution increase with the cumulant order.
CitationVlasenko, S., Mikhalychev, A. B., Karuseichyk, I. L., Lyakhov, D. A., Michels, D. L., & Mogilevtsev, D. (2020). Optimal correlation order in superresolution optical fluctuation microscopy. Physical Review A, 102(6). doi:10.1103/physreva.102.063507
PublisherAmerican Physical Society (APS)
JournalPhysical Review A