Examining histone modification crosstalk using immobilized libraries established from ligation-ready nucleosomes
AuthorsAparicio Pelaz, Diego
Mootz, Henning D.
KAUST DepartmentBioscience Program
Biological and Environmental Sciences and Engineering (BESE) Division
Permanent link to this recordhttp://hdl.handle.net/10754/664743
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Abstract280 different patterns of histone modifications were installed in preassembled nucleosomes using PTS and SML enabling screening of readout crosstalk.
CitationAparicio Pelaz, D., Yerkesh, Z., Kirchgäßner, S., Mahler, H., Kharchenko, V., Azhibek, D., … Fischle, W. (2020). Examining histone modification crosstalk using immobilized libraries established from ligation-ready nucleosomes. Chemical Science. doi:10.1039/d0sc03407j
SponsorsThis work was supported by the priority program SPP 1623 of the Deutsche Forschungsgemeinscha (DFG FI1513/3-1 to W. F. and SCHW1163/4-1 to D. S.) the Max Planck Society (W. F.), and intramural funds of King Abdullah University of Science and Technology (M. J., L. J. and W. F.). We thank members of the HDM group for help with establishing protein trans-splicing assays.
PublisherRoyal Society of Chemistry (RSC)
Except where otherwise noted, this item's license is described as This article is open access licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.