Examining histone modification crosstalk using immobilized libraries established from ligation-ready nucleosomes
Type
ArticleAuthors
Aparicio Pelaz, DiegoYerkesh, Zhadyra
Kirchgäßner, Sören
Mahler, Henriette
Kharchenko, Vladlena
Azhibek, Dulat
Jaremko, Mariusz
Mootz, Henning D.
Jaremko, Lukasz
Schwarzer, Dirk
Fischle, Wolfgang
KAUST Department
Bioscience ProgramBiological and Environmental Sciences and Engineering (BESE) Division
Bioscience
Date
2020Submitted Date
2020-06-19Permanent link to this record
http://hdl.handle.net/10754/664743Metadata
Show full item recordAbstract
280 different patterns of histone modifications were installed in preassembled nucleosomes using PTS and SML enabling screening of readout crosstalk.Citation
Aparicio Pelaz, D., Yerkesh, Z., Kirchgäßner, S., Mahler, H., Kharchenko, V., Azhibek, D., … Fischle, W. (2020). Examining histone modification crosstalk using immobilized libraries established from ligation-ready nucleosomes. Chemical Science. doi:10.1039/d0sc03407jSponsors
This work was supported by the priority program SPP 1623 of the Deutsche Forschungsgemeinscha (DFG FI1513/3-1 to W. F. and SCHW1163/4-1 to D. S.) the Max Planck Society (W. F.), and intramural funds of King Abdullah University of Science and Technology (M. J., L. J. and W. F.). We thank members of the HDM group for help with establishing protein trans-splicing assays.Publisher
Royal Society of Chemistry (RSC)Journal
Chemical ScienceAdditional Links
http://xlink.rsc.org/?DOI=D0SC03407JScopus Count
Except where otherwise noted, this item's license is described as This article is open access licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.