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dc.contributor.authorWang, Wu
dc.contributor.authorLee, Junho
dc.contributor.authorHarrou, Fouzi
dc.contributor.authorSun, Ying
dc.date.accessioned2020-08-16T09:35:14Z
dc.date.available2020-08-16T09:35:14Z
dc.date.issued2020
dc.identifier.citationWang, W., Lee, J., Harrou, F., & Sun, Y. (2020). Early Detection of Parkinson’s Disease Using Deep Learning and Machine Learning. IEEE Access, 1–1. doi:10.1109/access.2020.3016062
dc.identifier.issn2169-3536
dc.identifier.doi10.1109/ACCESS.2020.3016062
dc.identifier.urihttp://hdl.handle.net/10754/664603
dc.description.abstractAccurately detecting Parkinson’s disease (PD) at an early stage is certainly indispensable for slowing down its progress and providing patients the possibility of accessing to disease-modifying therapy. Towards this end, the premotor stage in PD should be carefully monitored. An innovative deep-learning technique is introduced to early uncover whether an individual is affected with PD or not based on premotor features. Specifically, to uncover PD at an early stage, several indicators have been considered in this study, including Rapid Eye Movement and olfactory loss, Cerebrospinal fluid data, and dopaminergic imaging markers. A comparison between the proposed deep learning model and twelve machine learning and ensemble learning methods based on relatively small data including 183 healthy individuals and 401 early PD patients shows the superior detection performance of the designed model, which achieves the highest accuracy, 96.45% on average. Besides detecting the PD, we also provide the feature importance on the PD detection process based on the Boosting method.
dc.publisherInstitute of Electrical and Electronics Engineers (IEEE)
dc.relation.urlhttps://ieeexplore.ieee.org/document/9165732/
dc.relation.urlhttps://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=9165732
dc.rightsThis work is licensed under a Creative Commons Attribution 4.0 License.
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectParkinson’s disease
dc.subjectDeep learning
dc.subjectEnsemble learning
dc.subjectEarly detection
dc.subjectPremotor features
dc.subjectFeatures importance
dc.titleEarly Detection of Parkinson’s Disease Using Deep Learning and Machine Learning
dc.typeArticle
dc.contributor.departmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
dc.contributor.departmentEnvironmental Statistics Group
dc.contributor.departmentStatistics Program
dc.identifier.journalIEEE Access
dc.eprint.versionPublisher's Version/PDF
dc.identifier.pages1-1
kaust.personWang, Wu
kaust.personLee, Junho
kaust.personHarrou, Fouzi
kaust.personSun, Ying
refterms.dateFOA2020-08-16T09:36:31Z


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