Methanol as the Hydrogen Source in the Selective Transfer Hydrogenation of Alkynes Enabled by a Manganese Pincer Complex

Embargo End Date
2021-07-28

Type
Article

Authors
Sklyaruk, Jan
Zubar, Viktoriia
Borghs, Jannik C.
Rueping, Magnus

KAUST Department
Chemical Science Program
KAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division

Online Publication Date
2020-07-28

Print Publication Date
2020-08-07

Date
2020-07-28

Abstract
The first base metal-catalyzed transfer hydrogenation of alkynes with methanol is described. An air and moisture stable manganese pincer complex catalyzes the reduction of a variety of different alkynes to the corresponding (Z)-olefins in high yields. The reaction is stereo- and chemoselective and scalable.

Citation
Sklyaruk, J., Zubar, V., Borghs, J. C., & Rueping, M. (2020). Methanol as the Hydrogen Source in the Selective Transfer Hydrogenation of Alkynes Enabled by a Manganese Pincer Complex. Organic Letters. doi:10.1021/acs.orglett.0c02151

Acknowledgements
J.S. thanks the VCI (Verband der Chemischen Industrie) for the Chemiefonds-Stipendium. J.C.B. acknowledges the DBU (Deutsche Bundesstiftung Umwelt) for the doctoral fellowship. This work was financially supported by the King Abdullah University of Science and Technology (KAUST), Saudi Arabia, Office of Sponsored Research (FCC/1/1974).

Publisher
American Chemical Society (ACS)

Journal
Organic Letters

DOI
10.1021/acs.orglett.0c02151

Additional Links
https://pubs.acs.org/doi/10.1021/acs.orglett.0c02151

Permanent link to this record