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PhD Dissertation_Andrea Bertoncini_Final.pdf
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Description:
PhD Dissertation
Embargo End Date:
2021-07-23
Type
ThesisAuthors
Bertoncini, Andrea
Advisors
Liberale, Carlo
Liberale, Carlo

Committee members
Ooi, Boon S.
Moser, Christophe
Program
BioscienceDate
2020-07Embargo End Date
2021-07-23Permanent link to this record
http://hdl.handle.net/10754/664372
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At the time of archiving, the student author of this thesis opted to temporarily restrict access to it. The full text of this thesis will become available to the public after the expiration of the embargo on 2021-07-23.Abstract
3D printing, also known as ”additive manufacturing”, indicates a set of fabrication techniques that build objects by adding material, typically layer by layer. The main advantages of 3D printing are unlimited shapes and geometry, fast prototyping, and cost-effective small scale production. Two-photon lithography (TPL) is a laserbased 3D printing technique with submicron resolution, that can be used to create miniaturized structures. One of the most compelling applications of TPL is the 3D printing of miniaturized optical elements with unprecedented complexity, small-scale and precision. This could be potentially beneficial in biophotonics, a multidisciplinary research field in which light-based techniques are used to study biological processes. My research has been aimed at demonstrating novel applications of 3D printing based on TPL to different biophotonic applications. In particular, here we show 3D printed micro-optical structures that enhance and/or enable novel functions in advanced biophotonics methods as two-photon microendoscopy, optical trapping and Stimulated Raman Scattering microscopy. Remarkably, the micro-optical structures presented in this thesis enable the implementation of advanced techniques in existing or simpler microscopy setups with little to no modification to the original setup. This possibility is essentially allowed by the unique miniaturization and in-situ 3D printing capabilities offered by TPL.Citation
Bertoncini, A. (2020). 3D Printed Micro-Optics for Biophotonics. KAUST Research Repository. https://doi.org/10.25781/KAUST-1X1K5ae974a485f413a2113503eed53cd6c53
10.25781/KAUST-1X1K5