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    3D Printed Micro-Optics for Biophotonics

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    Thumbnail
    Name:
    PhD Dissertation_Andrea Bertoncini_Final.pdf
    Size:
    31.96Mb
    Format:
    PDF
    Description:
    PhD Dissertation
    Embargo End Date:
    2021-07-23
    Download
    Type
    Thesis
    Authors
    Bertoncini, Andrea cc
    Advisors
    Liberale, Carlo cc
    Liberale, Carlo cc
    Committee members
    Ooi, Boon S. cc
    Moser, Christophe
    Program
    Bioscience
    KAUST Department
    Biological and Environmental Sciences and Engineering (BESE) Division
    Date
    2020-07
    Embargo End Date
    2021-07-23
    Permanent link to this record
    http://hdl.handle.net/10754/664372
    
    Metadata
    Show full item record
    Access Restrictions
    At the time of archiving, the student author of this thesis opted to temporarily restrict access to it. The full text of this thesis will become available to the public after the expiration of the embargo on 2021-07-23.
    Abstract
    3D printing, also known as ”additive manufacturing”, indicates a set of fabrication techniques that build objects by adding material, typically layer by layer. The main advantages of 3D printing are unlimited shapes and geometry, fast prototyping, and cost-effective small scale production. Two-photon lithography (TPL) is a laserbased 3D printing technique with submicron resolution, that can be used to create miniaturized structures. One of the most compelling applications of TPL is the 3D printing of miniaturized optical elements with unprecedented complexity, small-scale and precision. This could be potentially beneficial in biophotonics, a multidisciplinary research field in which light-based techniques are used to study biological processes. My research has been aimed at demonstrating novel applications of 3D printing based on TPL to different biophotonic applications. In particular, here we show 3D printed micro-optical structures that enhance and/or enable novel functions in advanced biophotonics methods as two-photon microendoscopy, optical trapping and Stimulated Raman Scattering microscopy. Remarkably, the micro-optical structures presented in this thesis enable the implementation of advanced techniques in existing or simpler microscopy setups with little to no modification to the original setup. This possibility is essentially allowed by the unique miniaturization and in-situ 3D printing capabilities offered by TPL.
    Citation
    Bertoncini, A. (2020). 3D Printed Micro-Optics for Biophotonics. KAUST Research Repository. https://doi.org/10.25781/KAUST-1X1K5
    DOI
    10.25781/KAUST-1X1K5
    ae974a485f413a2113503eed53cd6c53
    10.25781/KAUST-1X1K5
    Scopus Count
    Collections
    Biological and Environmental Sciences and Engineering (BESE) Division; Bioscience Program; Theses

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