Growth of large-scale MoS2 nanosheets on double layered ZnCo2O4 for real-time in situ H2S monitoring in live cells.
Salama, Khaled N.
KAUST DepartmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
Electrical Engineering Program
Permanent link to this recordhttp://hdl.handle.net/10754/664257
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AbstractThere is an urgent need to develop in situ sensors that monitor the continued release of H2S from biological systems to understand H2S-related pathology and pharmacology. For this purpose, we have developed a molybdenum disulfide supported double-layered zinc cobaltite modified carbon cloth electrode (MoS2-ZnCo2O4-ZnCo2O4) based electrocatalytic sensor. The results of our study suggest that the MoS2-ZnCo2O4-ZnCo2O4 electrode has excellent electrocatalytic ability to oxidize H2S at physiological pH, in a minimized overpotential (+0.20 vs. Ag/AgCl) with an amplified current signal. MoS2 grown on double-layered ZnCo2O4 showed relatively better surface properties and electrochemical properties than MoS2 grown on single-layered ZnCo2O4. The sensor delivered excellent analytical parameters, such as low detection limit (5 nM), wide linear range (10 nM-1000 μM), appreciable stability (94.3%) and high selectivity (2.5-fold). The practicality of the method was tested in several major biological fluids. The electrode monitors the dynamics of bacterial H2S in real-time for up to 5 h with good cell viability. Our research shows that MoS2-ZnCo2O4-ZnCo2O4/carbon cloth is a robust and sensitive electrode to understand how bacteria seek to adjust their defense strategies under exogenously induced stress conditions.
CitationMani, V., Selvaraj, S., Jeromiyas, N., Huang, S.-T., Ikeda, H., Hayakawa, Y., … Salama, K. N. (2020). Growth of large-scale MoS2 nanosheets on double layered ZnCo2O4 for real-time in situ H2S monitoring in live cells. Journal of Materials Chemistry B. doi:10.1039/d0tb01162b
SponsorsThis work was supported by the Ministry of Science and Technology (107-2113-M-027-007- and 108-2221-E-027-063-),Taiwan and King Abdullah University of Science and Technology (KAUST), Saudi Arabia. We also thank the support from Japanese Government MONBUKAGAKUSHO: MEXT Scholarship.
PublisherRoyal Society of Chemistry (RSC)
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