Intramolecularly stapled amphiphatic peptides via boron-sugar interaction
Type
ArticleAuthors
Kijewska, MonikaCzerwinska, Angelika
Al-Harthi, Samah

Wołczański, Grzegorz
Waliczek, Mateusz
Emwas, Abdul-Hamid M.
Jaremko, Mariusz

Jaremko, Lukasz

Stefanowicz, Piotr
Szewczuk, Zbigniew
KAUST Department
Bioscience ProgramNMR
Biological and Environmental Sciences and Engineering (BESE) Division
Date
2020Embargo End Date
2021-06-23Submitted Date
2020-04-10Permanent link to this record
http://hdl.handle.net/10754/663873
Metadata
Show full item recordAbstract
Amadori products (deoxyfructosyllysine derivatives) that can selectively interact with phenylboronic acids and borate ions were synthesized. The intramolecular interactions between the fructosyl moiety and phenylboronic acid incorporated in various positions of peptide chain was investigated using high-resolution mass spectrometry (HR-MS), circular dichroism (CD), and nuclear magnetic resonance (NMR).Citation
Kijewska, M., Czerwinska, A., Al-Harthi, S., Wołczański, G., Waliczek, M., Emwas, A.-H., … Szewczuk, Z. (2020). Intramolecularly stapled amphiphatic peptides via boron-sugar interaction. Chemical Communications. doi:10.1039/d0cc02603dSponsors
This work was supported by Grant No.UMO2015/19/B/ST5/00659 from the National Science Centre, Poland. The authors would like to thank Andrzej Reszka (ShimPol, Poland) for providing the Shimadzu LCMS-IT-TOF. LJ, MJ, SMA, and A-HE would like to thank the King Abdullah University of Science and Technology (KAUST) for financial support.Publisher
Royal Society of Chemistry (RSC)Journal
Chemical CommunicationsAdditional Links
http://pubs.rsc.org/en/Content/ArticleLanding/2020/CC/D0CC02603Dae974a485f413a2113503eed53cd6c53
10.1039/d0cc02603d