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dc.contributor.authorOrive-Miguel, David
dc.contributor.authorDi Sieno, Laura
dc.contributor.authorBehera, Anurag
dc.contributor.authorFerocino, Edoardo
dc.contributor.authorContini, Davide
dc.contributor.authorCondat, Laurent
dc.contributor.authorHervé, Lionel
dc.contributor.authorMars, Jérôme
dc.contributor.authorTorricelli, Alessandro
dc.contributor.authorPifferi, Antonio
dc.contributor.authorDalla Mora, Alberto
dc.date.accessioned2020-05-31T13:54:38Z
dc.date.available2020-05-31T13:54:38Z
dc.date.issued2020-05-15
dc.date.submitted2020-04-06
dc.identifier.citationOrive-Miguel, D., Di Sieno, L., Behera, A., Ferocino, E., Contini, D., Condat, L., … Dalla Mora, A. (2020). Real-Time Dual-Wavelength Time-Resolved Diffuse Optical Tomography System for Functional Brain Imaging Based on Probe-Hosted Silicon Photomultipliers. Sensors, 20(10), 2815. doi:10.3390/s20102815
dc.identifier.issn1424-8220
dc.identifier.pmid32429158
dc.identifier.doi10.3390/s20102815
dc.identifier.urihttp://hdl.handle.net/10754/662935
dc.description.abstractNear-infrared diffuse optical tomography is a non-invasive photonics-based imaging technology suited to functional brain imaging applications. Recent developments have proved that it is possible to build a compact time-domain diffuse optical tomography system based on silicon photomultipliers (SiPM) detectors. The system presented in this paper was equipped with the same eight SiPM probe-hosted detectors, but was upgraded with six injection fibers to shine the sample at several points. Moreover, an automatic switch was included enabling a complete measurement to be performed in less than one second. Further, the system was provided with a dual-wavelength ( 670 n m and 820 n m ) light source to quantify the oxy- and deoxy-hemoglobin concentration evolution in the tissue. This novel system was challenged against a solid phantom experiment, and two in-vivo tests, namely arm occlusion and motor cortex brain activation. The results show that the tomographic system makes it possible to follow the evolution of brain activation over time with a 1 s -resolution.
dc.description.sponsorshipThis research has received funding from the European Union’s Horizon 2020 Marie Skodowska-Curie Innovative Training Networks (ITN-ETN) programme, under Grant Agreement No. 675332 BitMap.
dc.publisherMDPI AG
dc.relation.urlhttps://www.mdpi.com/1424-8220/20/10/2815
dc.rightsThis is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleReal-Time Dual-Wavelength Time-Resolved Diffuse Optical Tomography System for Functional Brain Imaging Based on Probe-Hosted Silicon Photomultipliers.
dc.typeArticle
dc.contributor.departmentVisual Computing Center (VCC)
dc.identifier.journalSensors (Basel, Switzerland)
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionCEA, LETI, MINATEC Campus, F-38054 Grenoble, France.
dc.contributor.institutionPolitecnico di Milano, Dipartimento di Fisica, 20133 Milano, Italy.
dc.contributor.institutionUniversity Grenoble Alpes, CNRS, Grenoble INP, GIPSA-Lab, 38000 Grenoble, France.
dc.identifier.volume20
dc.identifier.issue10
dc.identifier.pages2815
kaust.personCondat, Laurent
dc.date.accepted2020-05-12
dc.identifier.eid2-s2.0-85084964279
refterms.dateFOA2020-05-31T13:55:11Z


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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.