Hydrogenation or Dehydrogenation of N-Containing Heterocycles Catalyzed by a Single Manganese Complex

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Type
Article
Authors
Zubar, Viktoriia
Borghs, Jannik C.
Rueping, Magnus cc
KAUST Department
Chemical Science Program
KAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Date
2020-05-04
Online Publication Date
2020-05-04
Print Publication Date
2020-05-15
Embargo End Date
2021-05-04
Submitted Date
2020-04-10
Permanent link to this record
http://hdl.handle.net/10754/662745

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Abstract
A highly chemoselective base-metal catalyzed hydrogenation and acceptorless dehydrogenation of N-heterocycles is presented. A well-defined Mn complex operates at low catalyst loading (as low as 2 mol %) and under mild reaction conditions. The described catalytic system tolerates various functional groups, and the corresponding reduced heterocycles can be obtained in high yields. Experimental studies indicate a metal-ligand cooperative catalysis mechanism
Citation
Zubar, V., Borghs, J. C., & Rueping, M. (2020). Hydrogenation or Dehydrogenation of N-Containing Heterocycles Catalyzed by a Single Manganese Complex. Organic Letters. doi:10.1021/acs.orglett.0c01273
Sponsors
This work was financially supported by the King Abdullah University of Science and Technology (KAUST), Saudi Arabia, Office of Sponsored Research (FCC/1/1974).
Publisher
American Chemical Society (ACS)
Journal
Organic Letters
DOI
10.1021/acs.orglett.0c01273
Additional Links
https://pubs.acs.org/doi/10.1021/acs.orglett.0c01273
Collections
Articles; Physical Science and Engineering (PSE) Division; Chemical Science Program; KAUST Catalysis Center (KCC)