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    Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017

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    Type
    Article
    Authors
    Guan, Qingtian cc
    Almutairi, Talal S.
    Alhalouli, Tahani
    Pain, Arnab cc
    Alasmari, Faisal
    KAUST Department
    Biological and Environmental Sciences and Engineering (BESE) Division
    Bioscience Program
    Pathogen Genomics Laboratory
    Date
    2020-02-04
    Online Publication Date
    2020-02-04
    Print Publication Date
    2020-03
    Permanent link to this record
    http://hdl.handle.net/10754/661704
    
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    Abstract
    Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to the multidrug-resistance phenotype clinically observed. Metagenomics sequencing can be used to identify multidrug-resistant M. leprae.
    Citation
    Guan, Q., Almutairi, T. S., Alhalouli, T., Pain, A., & Alasmari, F. (2020). Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017. Emerging Infectious Diseases, 26(3), 615–617. doi:10.3201/eid2603.190661
    Publisher
    Centers for Disease Control and Prevention (CDC)
    Journal
    Emerging Infectious Diseases
    DOI
    10.3201/eid2603.190661
    Additional Links
    http://wwwnc.cdc.gov/eid/article/26/3/19-0661_article.htm
    ae974a485f413a2113503eed53cd6c53
    10.3201/eid2603.190661
    Scopus Count
    Collections
    Articles; Biological and Environmental Science and Engineering (BESE) Division; Bioscience Program

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