Carotenoid biofortification in crop plants: citius, altius, fortius.
KAUST DepartmentBiological and Environmental Sciences and Engineering (BESE) Division
Desert Agriculture Initiative
Online Publication Date2020-02-15
Print Publication Date2020-11
Permanent link to this recordhttp://hdl.handle.net/10754/661583
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AbstractCarotenoids are indispensable for human health, required as precursors of vitamin A and efficient antioxidants. However, these plant pigments that play a vital role in photosynthesis are represented at insufficient levels in edible parts of several crops, which creates a need for increasing their content or optimizing their composition through biofortification. In particular, vitamin A deficiency, a severe health problem affecting the lives of millions in developing countries, has triggered the development of a series of high-provitamin A crops, including Golden Rice as the best-known example. Further carotenoid-biofortified crops have been generated by using genetic engineering approaches or through classical breeding. In this review, we depict carotenoid metabolism in plants and provide an update on the development of carotenoid-biofortified plants and their potential to meet needs and expectations. Furthermore, we discuss the possibility of using natural variation for carotenoid biofortification and the potential of gene editing tools. This article is part of a Special Issue entitled Carotenoids recent advances in cell and molecular biology edited by Johannes von Lintig and Loredana Quadro.
CitationZheng, X., Guliano, G., & Al-Babili, S. (2020). Carotenoid biofortification in crop plants: citius, altius, fortius. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 158664. doi:10.1016/j.bbalip.2020.158664
SponsorsWe thank Dr. Jianing Mi for valuable discussions. This work was supported by base line funding given to Salim Al-Babili from King Abdullah University for Science and Technology and by grants from the European Commission (projects G2P-SOL and Newcotiana) to Giovanni Giuliano.