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Type
ArticleKAUST Department
Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) DivisionElectrical Engineering Program
Integrated Nanotechnology Lab
KAUST Grant Number
OSR-2016-KKI-2880OSR-2015Sensors-2707
Date
2019-12-17Online Publication Date
2019-12-17Print Publication Date
2020-01Permanent link to this record
http://hdl.handle.net/10754/661481
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Show full item recordAbstract
Microfluidics is a continuously growing field with potential not only in the fields of medical, chemical, and bioanalysis, but also in the domains of optics and information technology. Here, a pressure-driven 3D microfluidic chip is demonstrated with multiple logic Boolean functions. The presence and absence of fluid at the output of the gates represent the binary signals 1 and 0, respectively. Therefore, the logic gates do not require a specially functionalized liquid to operate. The chip is based on a multilevel of poly(methyl methacrylate) (PMMA)-based polymeric sheets with aligned microchannels while a flexible polyimide-based sheet with a cantilever-like structure is embedded to enable a one-directional flow of the liquid. Several Boolean logic functions are realized (AND, OR, and XOR) using different fluids in addition to a half adder digital microfluidic circuit. The outputs of the logic gates are designed to be at different heights within the 3D chip to enable different pressure drops. The results show that the logic gates are operational for a specific range of flow rates, which is dependent on the microchannel dimensions, surface roughness, and fluid viscosity and therefore on their hydraulic resistance. The demonstrated approach enables simple cascading of logic gates for large-scale microfluidic computing systems.Citation
El-Atab, N., Canas, J. C., & Hussain, M. M. (2019). Pressure-Driven Two-Input 3D Microfluidic Logic Gates. Advanced Science, 7(2), 1903027. doi:10.1002/advs.201903027Sponsors
This publication is based upon work supported by the King Abdullah University of Science and Technology (KAUST) Office of Sponsored Research (OSR) under Award No. Sensor Innovation Initiative OSR-2015Sensors-2707 and KAUST-KFUPM Special Initiative OSR-2016-KKI-2880.Publisher
WileyJournal
Advanced ScienceAdditional Links
https://onlinelibrary.wiley.com/doi/abs/10.1002/advs.202070007ae974a485f413a2113503eed53cd6c53
10.1002/advs.201903027
Scopus Count
Except where otherwise noted, this item's license is described as This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.