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dc.contributor.authorTang, Xiaoyan
dc.contributor.authorWestlie, Andrea
dc.contributor.authorCaporaso, Lucia
dc.contributor.authorCavallo, Luigi
dc.contributor.authorFalivene, Laula
dc.contributor.authorChen, Eugene Y-X
dc.date.accessioned2020-02-03T06:37:00Z
dc.date.available2020-02-03T06:37:00Z
dc.date.issued2020-03-05
dc.date.submitted2019-12-21
dc.identifier.citationTang, X., Westlie, A., Caporaso, L., Cavallo, L., Falivene, L., & Chen, E. Y.-X. (2020). Biodegradable Polyhydroxyalkanoates by Stereoselective Copolymerization of Racemic Diolides: Stereocontrol Mechanism and Polyolefin-Like Properties. Angewandte Chemie International Edition. doi:10.1002/anie.201916415
dc.identifier.doi10.1002/anie.201916415
dc.identifier.doi10.1002/ange.201916415
dc.identifier.urihttp://hdl.handle.net/10754/661353
dc.description.abstractBacterial polyhydroxyalkanoates (PHAs) are a unique class of biodegradable polymers due to their biodegradability in ambient environments and structural diversity enabled by side-chain groups. However, the biosynthesis of PHAs is slow and expensive, limiting their broader applications as commodity plastics. To overcome such limitation, the catalyzed chemical synthesis of bacterial PHAs has been developed via the metal-catalyzed stereoselective ring-opening (co)polymerization of racemic cyclic diolides ( rac-8DL R , R = alkyl group). In this combined experimental and computational study, polymerization kinetics, stereocontrol mechanism, copolymerization characteristics, and the resulting PHAs' properties have been examined. Most notably, stereoselective copolymerizations of  rac-8DL Me with  rac-8DL R (R = Et, Bu) have yielded high-molecular-weight, crystalline isotactic PHA copolymers that are hard, ductile, and tough plastics, and exhibit polyolefin-like thermal and mechanical properties.
dc.description.sponsorshipThis work was supported by the US National Science Foundation (NSF-1664915) for the study carried out at Colorado State University. The computational study used the resources of the King Abdullah University of Science and Technology (KAUST) Super-computing Laboratory (KSL).
dc.publisherWiley
dc.relation.urlhttp://doi.wiley.com/10.1002/anie.201916415
dc.rightsArchived with thanks to Angewandte Chemie (International ed. in English)
dc.titleBiodegradable Polyhydroxyalkanoates by Stereoselective Copolymerization of Racemic Diolides: Stereocontrol Mechanism and Polyolefin-Like Properties.
dc.typeArticle
dc.contributor.departmentChemical Science Program
dc.contributor.departmentKAUST Catalysis Center (KCC)
dc.contributor.departmentKing Abdullah University of Science and Technology, Physcial Science, SAUDI ARABIA.
dc.contributor.departmentPhysical Science and Engineering (PSE) Division
dc.identifier.journalAngewandte Chemie (International ed. in English)
dc.rights.embargodate2021-01-29
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionColorado State University, Chemistry, UNITED STATES.
dc.contributor.institutionUniversity of Salerno, Chemistry, ITALY.
dc.contributor.institutionColorado State University, Chemistry, 1301 Centre Avenue, 80523-1872, Fort Collins, UNITED STATES.
kaust.personCavallo, Luigi
kaust.personFalivene, Laula
dc.date.accepted2020-01-27
dc.relation.issupplementedbyDOI:10.5517/ccdc.csd.cc24707n
refterms.dateFOA2020-02-03T06:38:53Z
display.relations<b>Is Supplemented By:</b><br/> <ul><li><i>[Dataset]</i> <br/> Tang, Xiaoyan, Westlie, Andrea H., Caporaso, Lucia, Cavallo, Luigi, Falivene, Laura, &amp; Chen, Eugene Y.-X. (2020). <i>CCDC 1972940: Experimental Crystal Structure Determination</i> [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/CCDC.CSD.CC24707N. DOI: <a href="https://doi.org/10.5517/ccdc.csd.cc24707n" >10.5517/ccdc.csd.cc24707n</a> Handle: <a href="http://hdl.handle.net/10754/664842" >10754/664842</a></a></li></ul>
dc.date.published-online2020-03-05
dc.date.published-print2020-05-11


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