Hydride Transfer Enables the Nickel-Catalyzed ipso-Borylation and Silylation of Aldehydes
Type
ArticleKAUST Department
Chemical Science ProgramKAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Date
2019-12-09Online Publication Date
2019-12-09Print Publication Date
2020-01-07Permanent link to this record
http://hdl.handle.net/10754/660921
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Show full item recordAbstract
Nickel-catalyzed ipso-borylations and silylations of aldehydes are described for the first time. The new functional-group interconversion protocol is characterized by its scalability, functional-group tolerance and wide substrate scope, including examples of late-stage functionalization of complex molecules. The key for the successful reaction outcome is the use of a ketone as a hydride acceptor that intercepts the nickel hydride to undergo a reductive pathway, thus allowing formation of the desired C−B and C−Si bonds.Citation
Srimontree, W., Guo, L., & Rueping, M. (2019). Hydride Transfer Enables the Nickel-Catalyzed ipso -Borylation and Silylation of Aldehydes. Chemistry – A European Journal. doi:10.1002/chem.201904842Sponsors
This research was supported by King Abdullah University of Science and Technology (KAUST) Office of Sponsored Research under award number URF/1/3030-01.Publisher
WileyJournal
Chemistry - A European JournalAdditional Links
https://onlinelibrary.wiley.com/doi/abs/10.1002/chem.201904842https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/chem.201904842
ae974a485f413a2113503eed53cd6c53
10.1002/chem.201904842
Scopus Count
Except where otherwise noted, this item's license is described as Archived with thanks to Chemistry - A European Journal