First report of Klebsiella quasipneumoniae harboring blaKPC-2 in Saudi Arabia
Antony, Chakkiath Paul
Althaqafi, Abdulhakeem O.
Alhaj-Hussein, Baraa T.
Zowawi, Hosam M.
KAUST DepartmentBioscience Program
Pathogen Genomics Laboratory, Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia
Red Sea Research Center, Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia
Biological and Environmental Sciences and Engineering (BESE) Division
Online Publication Date2019-12-19
Print Publication Date2019-12
Permanent link to this recordhttp://hdl.handle.net/10754/660869
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AbstractNosocomial infections caused by multi-drug resistant Enterobacteriaceae are a global public health threat that ought to be promptly identified, reported, and addressed accurately. Many carbapenem-resistant Enterobacteriaceae-associated genes have been identified in Saudi Arabia but not the endemic Klebsiella pneumoniae carbapenemases (KPCs), which are encoded by blaKPC-type genes. KPCs are known for their exceptional spreading potential.
CitationHala, S., Antony, C. P., Alshehri, M., Althaqafi, A. O., Alsaedi, A., Mufti, A., … Pain, A. (2019). First report of Klebsiella quasipneumoniae harboring blaKPC-2 in Saudi Arabia. Antimicrobial Resistance & Infection Control, 8(1). doi:10.1186/s13756-019-0653-9
SponsorsWe thank the infectious disease department and the pathology laboratory at King Khaled hospital in the Ministry of the National Guards – Health Affairs western region for their support of surveillance research. We also would like to thank the Bioscience core lab in KAUST for their help with the sequencing. We also thank Fathia Ben Rached, Malak Haidar, Qingtian Guan, and Sara Mfarrej from KAUST Microbial Genomics Laboratory for their technical help. We thank the team of curators at the Institut Pasteur MLST system (Paris, France) for importing novel alleles, profiles and/or isolates at http://bigsdb.pasteur.fr.
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Title: First report of KPC-2-producing Klebsiella quasipneumoniae in Saudi Arabia by whole-genome sequencing. Publication Date: 2019-03-05. bioproject: PRJEB30599 Handle: 10754/666827
Hala, Sharif; Antony, Chakkiath Paul; Alshehri, Mohammed; Alsaedi, Asim; Al Thaqafi, Abdulhakeem O.; Mufti, Areej; Kaaki, Mai; Alhaj-Hussein, Baraa T.; Zowawi, Hosam Mamoon; Al-Amri, Abdulfattah; Pain, A. (2019). Emergence of Klebsiella quasipneumoniae harboring blaKPC-2 in Saudi Arabia [Data set]. Zenodo. https://doi.org/10.5281/ZENODO.2583210. DOI: 10.5281/zenodo.2583210 Handle: 10754/667912
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