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    3D nanoprinted high NA ultra-compact catadioptric lens for efficient collection in forward detection configuration microscopy

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    Name:
    CLEO-Europe_SRSlens-Abstract.pdf
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    351.7Kb
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    PDF
    Description:
    Accepted manuscript
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    Type
    Conference Paper
    Authors
    Bertoncini, Andrea cc
    Laptenok, Siarhei P.
    Rajamanickam, Vijayakumar Palanisamy
    Liberale, Carlo cc
    KAUST Department
    Bioscience Program
    King Abdullah Univiversity of Science and Technology, Thuwal, Saudi Arabia
    Biological and Environmental Sciences and Engineering (BESE) Division
    Date
    2019-10-17
    Online Publication Date
    2019-10-17
    Print Publication Date
    2019-06
    Permanent link to this record
    http://hdl.handle.net/10754/660616
    
    Metadata
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    Abstract
    In optical microscopies which implement a forward detection scheme such as Coherent Anti-stokes Raman Scattering (CARS), Stimulated Raman Scattering (SRS) or Second - and Third-Harmonic Generation, efficient detection is usually achieved by collecting the signal with high Numerical Aperture (NA) objectives. While the use of high-end well-corrected high-NA microscope objectives for excitation is necessary to achieve high resolution, to efficiently induce non-linear effects and to have excellent imaging capabilities, the detection optics only requires the collimation of the highly divergent beam coming from the excitation path. Moreover, high NA objectives feature short working distances which render them incompatible with top stage incubators, which are the solution of choice for controlled long term experiments on live cells. Among the mentioned techniques, SRS strictly requires the collection of the full excitation beam NA to avoid spurious background signal caused by cross phase modulation (XPM) which can spoil the sensitivity of the system [1].
    Citation
    Bertoncini, A., Laptenok, S. P., Rajamanickam, V. P., & Liberale, C. (2019). 3D Nanoprinted High NA Ultra-Compact Catadioptric Lens for Efficient Collection in Forward Detection Configuration Microscopy. 2019 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC). doi:10.1109/cleoe-eqec.2019.8872142
    Publisher
    Institute of Electrical and Electronics Engineers (IEEE)
    Conference/Event name
    2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019
    DOI
    10.1109/CLEOE-EQEC.2019.8872142
    Additional Links
    https://ieeexplore.ieee.org/document/8872142/
    ae974a485f413a2113503eed53cd6c53
    10.1109/CLEOE-EQEC.2019.8872142
    Scopus Count
    Collections
    Conference Papers; Biological and Environmental Sciences and Engineering (BESE) Division; Bioscience Program

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