Nickel-catalyzed exo-selective hydroacylation/Suzuki cross-coupling reaction.
KAUST DepartmentChemical Science Program
KAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Embargo End Date2020-11-29
Permanent link to this recordhttp://hdl.handle.net/10754/660487
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AbstractThe first nickel-catalyzed intramolecular hydroacylation/Suzuki cross coupling cascade of o-allylbenzaldehydes with a broad range of phenylboronic acid neopentyl glycol esters has been developed. This strategy shows high regioselectivity and step economy in the construction of two C-C bonds via aldehyde C-H bond activation, affording valuable indanones with high efficiency.
CitationLee, S.-C., Guo, L., & Rueping, M. (2019). Nickel-catalyzed exo-selective hydroacylation/Suzuki cross-coupling reaction. Chemical Communications. doi:10.1039/c9cc07558e
PublisherRoyal Society of Chemistry (RSC)