Nickel-catalyzed exo-selective hydroacylation/Suzuki cross-coupling reaction.
Type
ArticleKAUST Department
Chemical Science ProgramKAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Date
2019Embargo End Date
2020-11-29Permanent link to this record
http://hdl.handle.net/10754/660487
Metadata
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The first nickel-catalyzed intramolecular hydroacylation/Suzuki cross coupling cascade of o-allylbenzaldehydes with a broad range of phenylboronic acid neopentyl glycol esters has been developed. This strategy shows high regioselectivity and step economy in the construction of two C-C bonds via aldehyde C-H bond activation, affording valuable indanones with high efficiency.Citation
Lee, S.-C., Guo, L., & Rueping, M. (2019). Nickel-catalyzed exo-selective hydroacylation/Suzuki cross-coupling reaction. Chemical Communications. doi:10.1039/c9cc07558ePublisher
Royal Society of Chemistry (RSC)Additional Links
http://xlink.rsc.org/?DOI=C9CC07558Eae974a485f413a2113503eed53cd6c53
10.1039/c9cc07558e