KAUST DepartmentChemical Science Program
KAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Embargo End Date2020-11-08
Permanent link to this recordhttp://hdl.handle.net/10754/660228
MetadataShow full item record
AbstractAn unprecedented nickel-catalyzed decarbonylative silylation via CO extrusion intramolecular recombination fragment coupling of unstrained and nondirecting group-Assisted silyl ketones is described. The inexpensive and readily available catalyst performs under mild reaction conditions and enables the synthesis of structurally diverse arylsilanes, including heterocyclic and natural product derivatives.
CitationSrimontree, W., Lakornwong, W., & Rueping, M. (2019). Nickel-Catalyzed Synthesis of Silanes from Silyl Ketones. Organic Letters. doi:10.1021/acs.orglett.9b03487
SponsorsW.L. was supported by the Thailand Research Fund through the Royal Golden Jubilee Ph.D. Program for the one-year exchange fellowship to RWTH-Aachen University. We thank Tengfei Ji for performing the large scale experiment.
PublisherAmerican Chemical Society (ACS)