KAUST DepartmentElectrical Engineering Program
Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia
Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
Online Publication Date2019-08-22
Print Publication Date2019-06
Permanent link to this recordhttp://hdl.handle.net/10754/658662
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AbstractA miniaturized drug delivery system suitable for in-vivo biomedical applications is presented. The system consists of an electrolytic pump driving a micro bellows membrane as an actuator for delivery through microneedles. A two-photon polymerization 3D printing technique was used to fabricate a reservoir equipped with microneedles. Analytical characterization of the flow rate through the microneedles showed an outgoing flow rate ranging from 63 μL/min to 520 μL/min for an applied pressure of 0.1 to 1 kPa. The assembled system with an overall size of 3.9 mm × 2.1 mm × 2 mm achieved delivery of 4 ± 0.5 μL within 12 seconds of actuation. A penetration test of the microneedle into a skin-like material confirms its potential for transdermal delivery.
CitationMoussi, K., Bukhamsin, A., & Kosel, J. (2019). Implantable 3D Printed Drug Delivery System. 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII). doi:10.1109/transducers.2019.8808496
SponsorsThis work was funded and supported by King Abdullah University of Science and Technology (KAUST).
Conference/Event name20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII