Membrane-Free Detection of Metal Cations with an Organic Electrochemical Transistor
Akhtar, Mahmood Hassan
KAUST DepartmentBiological and Environmental Sciences and Engineering (BESE) Division
Chemical Science Program
Environmental Science and Engineering Program
KAUST Solar Center (KSC)
King Abdullah University of Science and Technology (KAUST)Biological and Environmental Science and Engineering Thuwal 23955-6900 Saudi Arabia
Physical Science and Engineering (PSE) Division
KAUST Grant NumberOSR-2016-CRG5-3003
Embargo End Date2020-08-26
Permanent link to this recordhttp://hdl.handle.net/10754/656659
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AbstractAlkali-metal ions, particularly sodium (Na+) and potassium (K+), are the messengers of living cells, governing a cascade of physiological processes through the action of ion channels. Devices that can monitor, in real time, the concentrations of these cations in aqueous media are in demand not only for the study of cellular machinery, but also to detect conditions in the human body that lead to electrolyte imbalance. In this work, conducting polymers are developed that respond rapidly and selectively to varying concentrations of Na+ and K+ in aqueous media. These polymer films, bearing crown-ether-functionalized thiophene units specific to either Na+ or K+, generate an electrical output proportional to the cation type and concentration. Using electropolymerization, the ion-selective polymers are integrated as the gate electrode of an organic electrochemical transistor (OECT). The OECT current changes with respect to the concentration of the ion to which the polymer electrode is selective. Designed as a single, miniaturized chip, the OECT enables the selective detection of the cations within a physiologically relevant range. These electrochemical ion sensors require neither ion-selective membranes nor a reference electrode to operate and have the potential to surpass existing technologies for the detection of alkali-metal ions in aqueous media.
CitationWustoni, S., Combe, C., Ohayon, D., Akhtar, M. H., McCulloch, I., & Inal, S. (2019). Membrane-Free Detection of Metal Cations with an Organic Electrochemical Transistor. Advanced Functional Materials, 1904403. doi:10.1002/adfm.201904403
SponsorsThis research was supported by King Abdullah University of Science and Technology (KAUST) Office of Sponsored Research Competitive Research Grants (CRG) OSR award number OSR-2016-CRG5-3003 to S.I. and I.M. Figure 1, inset of Figure 2a, and TOC illustration were produced by Xavier Pita, scientific illustrator at KAUST.
JournalAdvanced Functional Materials