Phosphorylation regulates the activity of INDETERMINATE-DOMAIN (IDD/BIRD) proteins in response to diverse environmental conditions.
Type
ArticleKAUST Department
Desert Agriculture InitiativeBiological and Environmental Sciences and Engineering (BESE) Division
Plant Science
KAUST Grant Number
BAS/1/1062Date
2019-07-17Embargo End Date
2020-07-18Permanent link to this record
http://hdl.handle.net/10754/656462
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Show full item recordAbstract
INDETERMINATE-DOMAIN proteins (IDDs) belong to a diverse plant-specific family of transcriptional regulators that coordinate distinct functions during plant growth and development. The functions of several of these IDD members are transcriptionally regulated, but so far nothing is known about the regulation at the post-translational level in spite of the fact that post-translational modifications of these proteins have been reported in several large-scale proteomics studies. Recently, we showed that IDD4 is a repressor of basal immunity and its characteristic traits are predominantly determined by the phosphorylation at two distinct phosphorylation sites. This finding prompted us to comprehensively review phosphorylation of the various IDD members from the plethora of phosphoproteomics studies demonstrating the post-translational modification of IDDs at highly conserved sites under various experimental conditions. We reckon that the phosphorylation of IDDs is an underrated mechanistic aspect in their regulation and we postulate their importance in IDD/BIRD functioning.Citation
Völz, R., Rayapuram, N., & Hirt, H. (2019). Phosphorylation regulates the activity of INDETERMINATE-DOMAIN (IDD/BIRD) proteins in response to diverse environmental conditions. Plant Signaling & Behavior, 1–6. doi:10.1080/15592324.2019.1642037Sponsors
This work was supported by the King Abdullah University of Science and Technology [BAS/1/1062]Publisher
Informa UK LimitedJournal
Plant signaling & behaviorAdditional Links
https://www.tandfonline.com/doi/full/10.1080/15592324.2019.1642037ae974a485f413a2113503eed53cd6c53
10.1080/15592324.2019.1642037