Methyl phenlactonoates are efficient strigolactone analogs with simple structure.
Type
ArticleAuthors
Jamil, Muhammad
Kountche, Boubacar Amadou

Haider, Imran

Guo, Xiujie
Ntui, Valentine Otang
Jia, Kunpeng

Ali, Shawkat

Hameed, Umar S
Nakamura, Hidemitsu
Lyu, Ying
Jiang, Kai
Hirabayashi, Kei
Tanokura, Masaru
Arold, Stefan T.

Asami, Tadao
Al-Babili, Salim

KAUST Department
Biological and Environmental Sciences and Engineering (BESE) DivisionBioscience Program
Computational Bioscience Research Center (CBRC)
Desert Agriculture Initiative
Plant Science
Date
2017Embargo End Date
2019-01-05Permanent link to this record
http://hdl.handle.net/10754/656438
Metadata
Show full item recordAbstract
Strigolactones (SLs) are a new class of phytohormones that also act as germination stimulants for root parasitic plants, such as Striga spp., and as branching factors for symbiotic arbuscular mycorrhizal fungi. Sources for natural SLs are very limited. Hence, efficient and simple SL analogs are needed for elucidating SL-related biological processes as well as for agricultural applications. Based on the structure of the non-canonical SL methyl carlactonoate, we developed a new, easy to synthesize series of analogs, termed methyl phenlactonoates (MPs), evaluated their efficacy in exerting different SL functions, and determined their affinity for SL receptors from rice and Striga hermonthica. Most of the MPs showed considerable activity in regulating plant architecture, triggering leaf senescence, and inducing parasitic seed germination. Moreover, some MPs outperformed GR24, a widely used SL analog with a complex structure, in exerting particular SL functions, such as modulating Arabidopsis roots architecture and inhibiting rice tillering. Thus, MPs will help in elucidating the functions of SLs and are promising candidates for agricultural applications. Moreover, MPs demonstrate that slight structural modifications clearly impact the efficiency in exerting particular SL functions, indicating that structural diversity of natural SLs may mirror a functional specificity.Citation
OUP accepted manuscript. (2017). Journal Of Experimental Botany. doi:10.1093/jxb/erx438Sponsors
This work was funded by the Bill & Melinda Gates Foundation grant OPP1136424 and King Abdullah University of Science and Technology. We highly appreciate the valuable comments of Dr Jonne Rodenburg and thank Dr Binne Zwanenburg for providing GR24, Dr Junko Kyozuka for providing seeds of the rice d mutants, and Dr Abdel Gabar Babiker for providing S. hermonthica seeds.Publisher
Oxford University Press (OUP)Journal
Journal of experimental botanyAdditional Links
https://academic.oup.com/jxb/article/69/9/2319/4781055ae974a485f413a2113503eed53cd6c53
10.1093/jxb/erx438
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