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dc.contributor.authorMadsen, Curtis
dc.contributor.authorGoñi Moreno, Angel
dc.contributor.authorP, Umesh
dc.contributor.authorPalchick, Zachary
dc.contributor.authorRoehner, Nicholas
dc.contributor.authorAtallah, Christian
dc.contributor.authorBartley, Bryan
dc.contributor.authorChoi, Kiri
dc.contributor.authorCox, Robert Sidney
dc.contributor.authorGorochowski, Thomas
dc.contributor.authorGrunberg, Raik
dc.contributor.authorMacklin, Chris
dc.contributor.authorMcLaughlin, James
dc.contributor.authorMeng, Xianwei
dc.contributor.authorNguyen, Tramy
dc.contributor.authorPocock, Matthew
dc.contributor.authorSamineni, Meher
dc.contributor.authorScott-Brown, James
dc.contributor.authorTarter, Ysis
dc.contributor.authorZhang, Michael
dc.contributor.authorZhang, Zhen
dc.contributor.authorZundel, Zach
dc.contributor.authorBeal, Jacob
dc.contributor.authorBissell, Michael
dc.contributor.authorClancy, Kevin
dc.contributor.authorGennari, John H
dc.contributor.authorMisirli, Goksel
dc.contributor.authorMyers, Chris
dc.contributor.authorOberortner, Ernst
dc.contributor.authorSauro, Herbert
dc.contributor.authorWipat, Anil
dc.date.accessioned2019-08-07T13:01:56Z
dc.date.available2019-08-07T13:01:56Z
dc.date.issued2019-06-14
dc.identifier.citationMadsen, C., Goñi Moreno, A., P, U., Palchick, Z., Roehner, N., Atallah, C., … Wipat, A. (2019). Synthetic Biology Open Language (SBOL) Version 2.3. Journal of Integrative Bioinformatics, 0(0). doi:10.1515/jib-2019-0025
dc.identifier.doi10.1515/jib-2019-0025
dc.identifier.urihttp://hdl.handle.net/10754/656407
dc.description.abstractSynthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. The field still faces substantial challenges, including long development times, high rates of failure, and poor reproducibility. One method to ameliorate these problems is to improve the exchange of information about designed systems between laboratories. The synthetic biology open language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing standards. This document details version 2.3.0 of SBOL, which builds upon version 2.2.0 published in last year's JIB Standards in Systems Biology special issue. In particular, SBOL 2.3.0 includes means of succinctly representing sequence modifications, such as insertion, deletion, and replacement, an extension to support organization and attachment of experimental data derived from designs, and an extension for describing numerical parameters of design elements. The new version also includes specifying types of synthetic biology activities, unambiguous locations for sequences with multiple encodings, refinement of a number of validation rules, improved figures and examples, and clarification on a number of issues related to the use of external ontology terms.
dc.publisherWalter de Gruyter GmbH
dc.relation.urlhttp://www.degruyter.com/view/j/jib.ahead-of-print/jib-2019-0025/jib-2019-0025.xml
dc.rightsThe BioBricks Foundation and all authors listed on this BBF RFC. This work is made available under the Creative Commons Attribution 4.0 International Public License. To view a copy of this license visit https://creativecommons.org/licenses/by/4.0/
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectSynthetic Biology
dc.subjectSynthetic Biology Open Language
dc.subjectStandards
dc.titleSynthetic Biology Open Language (SBOL) Version 2.3.
dc.typeArticle
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Division
dc.identifier.journalJournal of integrative bioinformatics
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionBoston University, Boston, MA, USA.
dc.contributor.institutionNewcastle University, Newcastle, UK.
dc.contributor.institutionKerala Technological University, Thiruvananthapuram, India.
dc.contributor.institutionZymergen, Emeryville, CA, USA.
dc.contributor.institutionRaytheon BBN Technologies, Cambridge, MA, USA.
dc.contributor.institutionUniversity of Washington, Seattle, WA, USA.
dc.contributor.institutionProspect Bio, Brisbane, CA, USA.
dc.contributor.institutionUniversity of Bristol, Bristol, UK.
dc.contributor.institutionAmyris, Inc., Emeryville, CA, USA.
dc.contributor.institutionDOE Joint Genome Institute, Walnut Creek, CA, USA.
dc.contributor.institutionUniversity of Utah, Salt Lake City, UT, USA.
dc.contributor.institutionTuring Ate My Hamster, Ltd., Newcastle, UK.
dc.contributor.institutionImperial College, London, UK.
dc.contributor.institutionUtah State University, Logan, UT, USA.
dc.contributor.institutionBioCoder Consulting, Carlsbad, CA, USA.
dc.contributor.institutionKeele University, Keele, Staffordshire, UK.
kaust.personGrunberg, Raik
refterms.dateFOA2019-08-07T13:02:44Z
dc.date.published-online2019-06-14
dc.date.published-print2019-06-13


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The BioBricks Foundation and all authors listed on this BBF RFC. This work is made available under the Creative Commons Attribution 4.0 International Public License. To view a copy of this license visit https://creativecommons.org/licenses/by/4.0/
Except where otherwise noted, this item's license is described as The BioBricks Foundation and all authors listed on this BBF RFC. This work is made available under the Creative Commons Attribution 4.0 International Public License. To view a copy of this license visit https://creativecommons.org/licenses/by/4.0/