Electrochemical and Scalable Dehydrogenative C(sp 3 )−H Amination via Remote Hydrogen Atom Transfer in Batch and Continuous Flow
| dc.contributor.author | Nikolaienko, Pavlo | |
| dc.contributor.author | Jentsch, Marc | |
| dc.contributor.author | Kale, Ajit P. | |
| dc.contributor.author | Cai, Yunfei | |
| dc.contributor.author | Rueping, Magnus | |
| dc.date.accessioned | 2019-05-29T06:39:56Z | |
| dc.date.available | 2019-05-29T06:39:56Z | |
| dc.date.issued | 2019-05-02 | |
| dc.identifier.citation | Nikolaienko P, Jentsch M, Kale AP, Cai Y, Rueping M (2019) Electrochemical and Scalable Dehydrogenative C(sp 3 )−H Amination via Remote Hydrogen Atom Transfer in Batch and Continuous Flow. Chemistry – A European Journal 25: 7177–7184. Available: http://dx.doi.org/10.1002/chem.201806092. | |
| dc.identifier.issn | 0947-6539 | |
| dc.identifier.issn | 1521-3765 | |
| dc.identifier.doi | 10.1002/chem.201806092 | |
| dc.identifier.uri | http://hdl.handle.net/10754/653109 | |
| dc.description.abstract | A hydrogen atom transfer-directed electrochemical intramolecular C−H amination has been developed in which the N-radical species are generated at the anode, and the base required for the reaction is generated at the cathode. A broad range of valuable pyrrolidines were prepared in good yields and with high chemoselectivity. The reaction was easily scaled up in both batch and continuous flow systems. | |
| dc.description.sponsorship | This work was financially supported by the King Abdullah University of Science and Technology (KAUST), Saudi Arabia, Office of Sponsored Research (URF/1/1974-04-01). | |
| dc.publisher | Wiley | |
| dc.relation.url | https://onlinelibrary.wiley.com/doi/full/10.1002/chem.201806092 | |
| dc.rights | Archived with thanks to Chemistry – A European Journal | |
| dc.subject | 1,5-HAT | |
| dc.subject | amination | |
| dc.subject | electrosynthesis | |
| dc.subject | flow electrolysis | |
| dc.subject | pyrrolidines | |
| dc.title | Electrochemical and Scalable Dehydrogenative C(sp 3 )−H Amination via Remote Hydrogen Atom Transfer in Batch and Continuous Flow | |
| dc.type | Article | |
| dc.contributor.department | KAUST Catalysis Center (KCC) | |
| dc.identifier.journal | Chemistry – A European Journal | |
| dc.eprint.version | Post-print | |
| dc.contributor.institution | Institute of Organic ChemistryRWTH-Aachen University Landoltweg 1 52074 Aachen Germany | |
| kaust.person | Nikolaienko, Pavlo | |
| kaust.person | Kale, Ajit P. | |
| kaust.person | Cai, Yunfei | |
| kaust.person | Rueping, Magnus | |
| kaust.grant.number | URF/1/1974-04-01 | |
| refterms.dateFOA | 2020-05-02T00:00:00Z | |
| dc.date.published-online | 2019-05-02 | |
| dc.date.published-print | 2019-05-23 |
